Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

Sadao Suga, Tetsushi Yoshikawa, Yoshizo Asano, Toshihiko Nakashima, Takehiko Yazaki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

Original languageEnglish
Pages (from-to)404-408
Number of pages5
JournalPediatrics International
Volume34
Issue number4
DOIs
Publication statusPublished - 01-01-1992

Fingerprint

Viremia
Measles
Antibody Formation
Blood Cells
Neutralizing Antibodies
Fever
Antibodies

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Suga, Sadao ; Yoshikawa, Tetsushi ; Asano, Yoshizo ; Nakashima, Toshihiko ; Yazaki, Takehiko. / Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles. In: Pediatrics International. 1992 ; Vol. 34, No. 4. pp. 404-408.
@article{1a2549d1ed7345dea3af50c4745cc159,
title = "Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles",
abstract = "Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.",
author = "Sadao Suga and Tetsushi Yoshikawa and Yoshizo Asano and Toshihiko Nakashima and Takehiko Yazaki",
year = "1992",
month = "1",
day = "1",
doi = "10.1111/j.1442-200X.1992.tb00979.x",
language = "English",
volume = "34",
pages = "404--408",
journal = "Pediatrics International",
issn = "1328-8067",
publisher = "Wiley-Blackwell",
number = "4",

}

Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles. / Suga, Sadao; Yoshikawa, Tetsushi; Asano, Yoshizo; Nakashima, Toshihiko; Yazaki, Takehiko.

In: Pediatrics International, Vol. 34, No. 4, 01.01.1992, p. 404-408.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

AU - Suga, Sadao

AU - Yoshikawa, Tetsushi

AU - Asano, Yoshizo

AU - Nakashima, Toshihiko

AU - Yazaki, Takehiko

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

AB - Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

UR - http://www.scopus.com/inward/record.url?scp=0026713383&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026713383&partnerID=8YFLogxK

U2 - 10.1111/j.1442-200X.1992.tb00979.x

DO - 10.1111/j.1442-200X.1992.tb00979.x

M3 - Article

C2 - 1414329

AN - SCOPUS:0026713383

VL - 34

SP - 404

EP - 408

JO - Pediatrics International

JF - Pediatrics International

SN - 1328-8067

IS - 4

ER -