Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

Sadao Suga; Tetsushi Yoshikawa; Yoshizo Asano; Toshihiko Nakashima; Takehiko Yazaki

doi:10.1111/j.1442-200X.1992.tb00979.x

Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

Sadao Suga, Tetsushi Yoshikawa, Yoshizo Asano, Toshihiko Nakashima, Takehiko Yazaki

Pediatrics

Research output: Contribution to journal › Article › peer-review

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Abstract

Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log₁₀, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

Original language	English
Pages (from-to)	404-408
Number of pages	5
Journal	Pediatrics International
Volume	34
Issue number	4
DOIs	https://doi.org/10.1111/j.1442-200X.1992.tb00979.x
Publication status	Published - 08-1992

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Pediatrics, Perinatology, and Child Health

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10.1111/j.1442-200X.1992.tb00979.x

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title = "Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles",

abstract = "Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.",

author = "Sadao Suga and Tetsushi Yoshikawa and Yoshizo Asano and Toshihiko Nakashima and Takehiko Yazaki",

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T1 - Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

AU - Suga, Sadao

AU - Yoshikawa, Tetsushi

AU - Asano, Yoshizo

AU - Nakashima, Toshihiko

AU - Yazaki, Takehiko

PY - 1992/8

Y1 - 1992/8

N2 - Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

AB - Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

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Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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