Abstract
An otherwise healthy 3-year-old girl developed severe varicella complicated by aseptic meningitis and received intravenous acyclovir (ACV) therapy. Her two siblings who were susceptible to varicella-zoster virus (VZV) and closely exposed to VZV in the family received oral ACV (45 or 54 mg/kg per day in four divided doses for 7 days) starting 8 days after onset of the index case for post-exposure prophylaxis of varicella. They showed only five or seven papules over the body without fever 12 days after onset of the index case, while they had one-third or half the level of antibody titer and equal sized skin reactions to VZV antigen of the index case 2.5 months later.
Original language | English |
---|---|
Pages (from-to) | 692-694 |
Number of pages | 3 |
Journal | Pediatrics International |
Volume | 38 |
Issue number | 6 |
DOIs | |
Publication status | Published - 12-1996 |
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health