Comparison of standardised mortality ratios for renal failure before and after the 2011 Great East Japan Earthquake and Tsunami

An analysis of national vital statistics

Rumi Tsukinoki, Yoshitaka Murakami, Miyuki Kawado, Shuji Hashimoto

Research output: Contribution to journalArticle

Abstract

Objective The impact of the 2011 Great East Japan Earthquake on renal failure (RF) risk remains unclear. We examined the 1-year impact of this disaster on RF mortality. Setting This ecological study focused on the year before and after the earthquake. The data sources were national vital statistics (2010-2012), the national census (2010) and the Basic Resident Registration (2010-2012). Participants Our study included all residents in Iwate, Miyagi and Fukushima, 1 year before and after the earthquake. Primary and secondary outcome measures We calculated standardised mortality ratios (SMRs) for RF, chronic RF and acute RF. Postearthquake weekly SMRs were calculated using the number of RF deaths for the corresponding weeks in 2010 as a reference. The SMRs for RF were compared between the coastal and inland municipalities using kernel-weighted polynomial smoothing. Results There were 1290 RF deaths in the three prefectures during the year after the earthquake (chronic RF: 804 and acute RF: 236). The SMR for RF increased significantly in the first week after the earthquake in coastal areas (3.11; 95% CI: 1.84 to 4.37), but did not increase in inland areas (0.93; 95% CI: 0.47 to 1.38). A similar trend was observed for chronic RF (coastal: 4.0; 95% CI: 2.0 to 6.0; inland: 1.1; 95% CI: 0.4 to 1.7). SMRs for RF and chronic RF decreased over time and reached 1.0 approximately 20 weeks after the disaster. Changes in SMRs for acute RF were not apparent due to the low number of deaths. Conclusions Mortality due to RF and chronic RF, but not acute RF, increased in coastal areas after the earthquake. Chronic RF may have been exacerbated by disaster-induced sympathetic activation and poor management of renal dysfunction. Increased hypertension and damage to essential infrastructure and medical equipment may also have increased mortality in people with kidney disease.

Original languageEnglish
Article numbere023435
JournalBMJ Open
Volume8
Issue number12
DOIs
Publication statusPublished - 01-12-2018

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Tsunamis
Vital Statistics
Earthquakes
Renal Insufficiency
Japan
Chronic Kidney Failure
Mortality
Acute Kidney Injury
Disasters
Information Storage and Retrieval
Kidney Diseases
Censuses
Outcome Assessment (Health Care)
Hypertension
Kidney

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{0bb457ba903145168c28c3d2f089be58,
title = "Comparison of standardised mortality ratios for renal failure before and after the 2011 Great East Japan Earthquake and Tsunami: An analysis of national vital statistics",
abstract = "Objective The impact of the 2011 Great East Japan Earthquake on renal failure (RF) risk remains unclear. We examined the 1-year impact of this disaster on RF mortality. Setting This ecological study focused on the year before and after the earthquake. The data sources were national vital statistics (2010-2012), the national census (2010) and the Basic Resident Registration (2010-2012). Participants Our study included all residents in Iwate, Miyagi and Fukushima, 1 year before and after the earthquake. Primary and secondary outcome measures We calculated standardised mortality ratios (SMRs) for RF, chronic RF and acute RF. Postearthquake weekly SMRs were calculated using the number of RF deaths for the corresponding weeks in 2010 as a reference. The SMRs for RF were compared between the coastal and inland municipalities using kernel-weighted polynomial smoothing. Results There were 1290 RF deaths in the three prefectures during the year after the earthquake (chronic RF: 804 and acute RF: 236). The SMR for RF increased significantly in the first week after the earthquake in coastal areas (3.11; 95{\%} CI: 1.84 to 4.37), but did not increase in inland areas (0.93; 95{\%} CI: 0.47 to 1.38). A similar trend was observed for chronic RF (coastal: 4.0; 95{\%} CI: 2.0 to 6.0; inland: 1.1; 95{\%} CI: 0.4 to 1.7). SMRs for RF and chronic RF decreased over time and reached 1.0 approximately 20 weeks after the disaster. Changes in SMRs for acute RF were not apparent due to the low number of deaths. Conclusions Mortality due to RF and chronic RF, but not acute RF, increased in coastal areas after the earthquake. Chronic RF may have been exacerbated by disaster-induced sympathetic activation and poor management of renal dysfunction. Increased hypertension and damage to essential infrastructure and medical equipment may also have increased mortality in people with kidney disease.",
author = "Rumi Tsukinoki and Yoshitaka Murakami and Miyuki Kawado and Shuji Hashimoto",
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Comparison of standardised mortality ratios for renal failure before and after the 2011 Great East Japan Earthquake and Tsunami : An analysis of national vital statistics. / Tsukinoki, Rumi; Murakami, Yoshitaka; Kawado, Miyuki; Hashimoto, Shuji.

In: BMJ Open, Vol. 8, No. 12, e023435, 01.12.2018.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparison of standardised mortality ratios for renal failure before and after the 2011 Great East Japan Earthquake and Tsunami

T2 - An analysis of national vital statistics

AU - Tsukinoki, Rumi

AU - Murakami, Yoshitaka

AU - Kawado, Miyuki

AU - Hashimoto, Shuji

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Objective The impact of the 2011 Great East Japan Earthquake on renal failure (RF) risk remains unclear. We examined the 1-year impact of this disaster on RF mortality. Setting This ecological study focused on the year before and after the earthquake. The data sources were national vital statistics (2010-2012), the national census (2010) and the Basic Resident Registration (2010-2012). Participants Our study included all residents in Iwate, Miyagi and Fukushima, 1 year before and after the earthquake. Primary and secondary outcome measures We calculated standardised mortality ratios (SMRs) for RF, chronic RF and acute RF. Postearthquake weekly SMRs were calculated using the number of RF deaths for the corresponding weeks in 2010 as a reference. The SMRs for RF were compared between the coastal and inland municipalities using kernel-weighted polynomial smoothing. Results There were 1290 RF deaths in the three prefectures during the year after the earthquake (chronic RF: 804 and acute RF: 236). The SMR for RF increased significantly in the first week after the earthquake in coastal areas (3.11; 95% CI: 1.84 to 4.37), but did not increase in inland areas (0.93; 95% CI: 0.47 to 1.38). A similar trend was observed for chronic RF (coastal: 4.0; 95% CI: 2.0 to 6.0; inland: 1.1; 95% CI: 0.4 to 1.7). SMRs for RF and chronic RF decreased over time and reached 1.0 approximately 20 weeks after the disaster. Changes in SMRs for acute RF were not apparent due to the low number of deaths. Conclusions Mortality due to RF and chronic RF, but not acute RF, increased in coastal areas after the earthquake. Chronic RF may have been exacerbated by disaster-induced sympathetic activation and poor management of renal dysfunction. Increased hypertension and damage to essential infrastructure and medical equipment may also have increased mortality in people with kidney disease.

AB - Objective The impact of the 2011 Great East Japan Earthquake on renal failure (RF) risk remains unclear. We examined the 1-year impact of this disaster on RF mortality. Setting This ecological study focused on the year before and after the earthquake. The data sources were national vital statistics (2010-2012), the national census (2010) and the Basic Resident Registration (2010-2012). Participants Our study included all residents in Iwate, Miyagi and Fukushima, 1 year before and after the earthquake. Primary and secondary outcome measures We calculated standardised mortality ratios (SMRs) for RF, chronic RF and acute RF. Postearthquake weekly SMRs were calculated using the number of RF deaths for the corresponding weeks in 2010 as a reference. The SMRs for RF were compared between the coastal and inland municipalities using kernel-weighted polynomial smoothing. Results There were 1290 RF deaths in the three prefectures during the year after the earthquake (chronic RF: 804 and acute RF: 236). The SMR for RF increased significantly in the first week after the earthquake in coastal areas (3.11; 95% CI: 1.84 to 4.37), but did not increase in inland areas (0.93; 95% CI: 0.47 to 1.38). A similar trend was observed for chronic RF (coastal: 4.0; 95% CI: 2.0 to 6.0; inland: 1.1; 95% CI: 0.4 to 1.7). SMRs for RF and chronic RF decreased over time and reached 1.0 approximately 20 weeks after the disaster. Changes in SMRs for acute RF were not apparent due to the low number of deaths. Conclusions Mortality due to RF and chronic RF, but not acute RF, increased in coastal areas after the earthquake. Chronic RF may have been exacerbated by disaster-induced sympathetic activation and poor management of renal dysfunction. Increased hypertension and damage to essential infrastructure and medical equipment may also have increased mortality in people with kidney disease.

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