Complementary roles of whole-body diffusion-weighted MRI and 18F-FDG PET: The state of the art and potential applications

Thomas C. Kwee, Taro Takahara, Reiji Ochiai, Dow Mu Koh, Yoshiharu Ohno, Katsuyuki Nakanishi, Tetsu Niwa, Thomas L. Chenevert, Peter R. Luijten, Abass Alavi

Research output: Contribution to journalReview articlepeer-review

77 Citations (Scopus)


18F-FDG PET is an established functional imaging modality for the evaluation of human disease. Diffusion-weighted MRI (DWI) is another rapidly evolving functional imaging modality that can be used to evaluate oncologic and nononcologic lesions throughout the body. The information provided by 18F-FDG PET and DWI can be complementary, because the 2 methods are based on completely different biophysical underpinnings. This article will describe the basic principles, clinical applications, and limitations of DWI. In addition, the available evidence that correlates and compares 18F-FDG PET and DWI will be reviewed.

Original languageEnglish
Pages (from-to)1549-1558
Number of pages10
JournalJournal of Nuclear Medicine
Issue number10
Publication statusPublished - 01-10-2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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