Abstract
We sequenced a novel conjugative blaKPC-2-harboring IncN plasmid, pYD626E, from an Escherichia coli sequence type 648 strain previously identified in Pittsburgh, Pennsylvania. pYD626E was 72,800 bp long and carried four β-lactamase genes, blaKPC-2, blaSHV-12, blaLAP-1, and blaTEM-1. In addition, it harbored qnrS1 (fluoroquinolone resistance) and dfrA14 (trimethoprim resistance). The plasmid profile and clinical history supported the in vivo transfer of this plasmid between Klebsiella pneumoniae and Escherichia coli.
| Original language | English |
|---|---|
| Pages (from-to) | 6974-6977 |
| Number of pages | 4 |
| Journal | Antimicrobial agents and chemotherapy |
| Volume | 58 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 01-11-2014 |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases
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Li, J. J., Lee, C. S., Sheng, J. F., & Doi, Y. (2014). Complete sequence of a conjugative IncN plasmid harboring blaKPC-2, blaSHV-12, and qnrS1 from an escherichia coli sequence type 648 Strain. Antimicrobial agents and chemotherapy, 58(11), 6974-6977. https://doi.org/10.1128/AAC.03632-14