Abstract
We sequenced a novel conjugative blaKPC-2-harboring IncN plasmid, pYD626E, from an Escherichia coli sequence type 648 strain previously identified in Pittsburgh, Pennsylvania. pYD626E was 72,800 bp long and carried four β-lactamase genes, blaKPC-2, blaSHV-12, blaLAP-1, and blaTEM-1. In addition, it harbored qnrS1 (fluoroquinolone resistance) and dfrA14 (trimethoprim resistance). The plasmid profile and clinical history supported the in vivo transfer of this plasmid between Klebsiella pneumoniae and Escherichia coli.
| Original language | English |
|---|---|
| Pages (from-to) | 6974-6977 |
| Number of pages | 4 |
| Journal | Antimicrobial agents and chemotherapy |
| Volume | 58 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 01-11-2014 |
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All Science Journal Classification (ASJC) codes
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases
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Complete sequence of a conjugative IncN plasmid harboring blaKPC-2, blaSHV-12, and qnrS1 from an escherichia coli sequence type 648 Strain. / Li, Jun Jie; Lee, Chang Seop; Sheng, Ji Fang; Doi, Yohei.
In: Antimicrobial agents and chemotherapy, Vol. 58, No. 11, 01.11.2014, p. 6974-6977.Research output: Contribution to journal › Article
TY - JOUR
T1 - Complete sequence of a conjugative IncN plasmid harboring blaKPC-2, blaSHV-12, and qnrS1 from an escherichia coli sequence type 648 Strain
AU - Li, Jun Jie
AU - Lee, Chang Seop
AU - Sheng, Ji Fang
AU - Doi, Yohei
PY - 2014/11/1
Y1 - 2014/11/1
N2 - We sequenced a novel conjugative blaKPC-2-harboring IncN plasmid, pYD626E, from an Escherichia coli sequence type 648 strain previously identified in Pittsburgh, Pennsylvania. pYD626E was 72,800 bp long and carried four β-lactamase genes, blaKPC-2, blaSHV-12, blaLAP-1, and blaTEM-1. In addition, it harbored qnrS1 (fluoroquinolone resistance) and dfrA14 (trimethoprim resistance). The plasmid profile and clinical history supported the in vivo transfer of this plasmid between Klebsiella pneumoniae and Escherichia coli.
AB - We sequenced a novel conjugative blaKPC-2-harboring IncN plasmid, pYD626E, from an Escherichia coli sequence type 648 strain previously identified in Pittsburgh, Pennsylvania. pYD626E was 72,800 bp long and carried four β-lactamase genes, blaKPC-2, blaSHV-12, blaLAP-1, and blaTEM-1. In addition, it harbored qnrS1 (fluoroquinolone resistance) and dfrA14 (trimethoprim resistance). The plasmid profile and clinical history supported the in vivo transfer of this plasmid between Klebsiella pneumoniae and Escherichia coli.
UR - http://www.scopus.com/inward/record.url?scp=84908592671&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908592671&partnerID=8YFLogxK
U2 - 10.1128/AAC.03632-14
DO - 10.1128/AAC.03632-14
M3 - Article
C2 - 25182636
AN - SCOPUS:84908592671
VL - 58
SP - 6974
EP - 6977
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 11
ER -