Complete sequences of multidrug resistance plasmids bearing rmtD1 and rmtD2 16S rRNA methyltransferase genes

Maria Fernanda C. Bueno, Gabriela R. Francisco, Doroti De Oliveira Garcia, Yohei Doi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Complete nucleotide sequences were determined for two plasmids bearing rmtD group 16S rRNA methyltransferase genes. pKp64/11 was 78 kb in size, belonged to the IncL/M group, and harbored blaTEM-1b, sul1, qacEΔ1, dfrA22, and rmtD1 across two multidrug resistance regions (MRRs). pKp368/10 was 170 kb in size, belonged to the IncA/C group, and harbored acrB, sul1, qacEΔ1, ant(3")-Ia, aac(6')-Ib, cat, rmtD2, and blaCTXM-8 across three MRRs. The rmtD-containing regions shared a conserved motif, suggesting a common origin for the two rmtD alleles.

Original languageEnglish
Pages (from-to)1928-1931
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume60
Issue number3
DOIs
Publication statusPublished - 03-2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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