Complicated intra-abdominal infections in a worldwide context: An observational prospective study (CIAOW Study)

Massimo Sartelli, Fausto Catena, Luca Ansaloni, Ernest Moore, Mark Malangoni, George Velmahos, Raul Coimbra, Kaoru Koike, Ari Leppaniemi, Walter Biffl, Zsolt Balogh, Cino Bendinelli, Sanjay Gupta, Yoram Kluger, Ferdinando Agresta, Salomone di Saverio, Gregorio Tugnoli, Elio Jovine, Carlos Ordonez, Carlos Augusto GomesGerson Alves Pereira Junior, Kuo Ching Yuan, Miklosh Bala, Miroslav P. Peev, Yunfeng Cui, Sanjay Marwah, Sanoop Zachariah, Boris Sakakushev, Victor Kong, Adamu Ahmed, Ashraf Abbas, Ricardo Alessandro Teixeira Gonsaga, Gianluca Guercioni, Nereo Vettoretto, Elia Poiasina, Offir Ben-Ishay, Rafael Díaz-Nieto, Damien Massalou, Matej Skrovina, Ihor Gerych, Goran Augustin, Jakub Kenig, Vladimir Khokha, Cristian Tranà, Kenneth Yuh Yen Kok, Alain Chichom Mefire, Jae Gil Lee, Suk Kyung Hong, Helmut Alfredo Segovia Lohse, Wagih Ghnnam, Alfredo Verni, Varut Lohsiriwat, Boonying Siribumrungwong, Alberto Tavares, Gianluca Baiocchi, Koray Das, Julien Jarry, Maurice Zida, Norio Sato, Kiyoshi Murata, Tomohisa Shoko, Takayuki Irahara, Ahmed O. Hamedelneel, Noel Naidoo, Abdul Rashid Kayode Adesunkanmi, Yoshiro Kobe, A. K. Attri, Rajeev Sharma, Federico Coccolini, Tamer El Zalabany, Khalid Al Khalifa, Juan Sanjuan, Rita Barnabé, Wataru Ishii

Research output: Contribution to journalReview articlepeer-review

55 Citations (Scopus)


Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18-98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.

Original languageEnglish
Article number1
JournalWorld Journal of Emergency Surgery
Issue number1
Publication statusPublished - 03-01-2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Emergency Medicine


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