Concentration of roxithromycin in the lesions of acne vulgaris

H. Akamatsu, T. Horio

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Roxithromycin, a macrolide antibiotic, is used in the treatment of acne vulgaris, although there have been no reports on its concentration in lesions when administered orally. We investigated the concentration of roxithromycin in acne vulgaris lesions in five patients who received 150 mg roxithromycin orally twice daily for 2 weeks. The mean concentration of roxithromycin in the lesions was 0.54 μg/ml. These results suggest that roxithromycin accumulates at therapeutic levels in the pilosebaceous system.

Original languageEnglish
Pages (from-to)537-540
Number of pages4
JournalJournal of International Medical Research
Issue number6
Publication statusPublished - 2001

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cell Biology
  • Biochemistry, medical


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