Concentration of transforming growth factor-β2 in the aqueous humor

Kiyoyuki Majima, Naoki Yamamoto, Kouichirou Itonaga, Keiji Kiribuchi, Hiroko Inuzuka, Kyoko Haki

Research output: Contribution to journalArticlepeer-review


We quantitated the total transforming growth factor β2 (TGF - β2) in the aqueous humor obtained during cataract surgery. Measurement was made in 96 eyes of 96 patients. Their ages ranged from 17 to 88 years. The series comprised 73 eyes with no eye disease except cataract, 8 eyes under treatment for primary open-angle glaucoma, 10 eyes with diabetic retinopathy, and 5 eyes of atopic cataract. The TGF - β 2 value decreased along with advance of age. It was low in atopic cataract and was high in glaucoma and diabetic retinopathy with past history of panphotocoagulation. Due attention is necessary to the new findings that the total TGF - β2 value in cataractous eye is influenced by age, atopic cataract, and diabetic retinopathy treated by photocoagulation.

Original languageEnglish
Pages (from-to)61-64
Number of pages4
JournalJapanese Journal of Clinical Ophthalmology
Issue number1
Publication statusPublished - 2004

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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