Congenital Stationary Night Blindness With Negative Electroretinogram: A New Classification

Yozo Miyake, Katsuya Yagasaki, Masayuki Horiguchi, Yoshikatsu Kawase, Takako Kanda

Research output: Contribution to journalArticlepeer-review

406 Citations (Scopus)

Abstract

An analysis of 64 patients with congenital stationary night blindness showed that all had essentially normal fundi. Electroretinography (ERG) showed a normal a wave with extremely reduced b wave (negative type) when recorded with a single bright white stimulus in the dark. We classified these patients into two groups based on the evaluation of rod ERG and/ or psychophysical dark adaptation measured with an 11° test target at 15° in the upper part of the retina. One group (35 patients) lacked rod function (complete type) and the other group (20 patients) showed some rod function (incomplete type). Nine patients could not be classified. No pedigree showed a complete and incomplete type in one family. Differences between the two groups in refractive error, photopic function, and oscillatory potentials in the ERG suggest a different pathogenesis. Our analysis may provide a new classification of congenital stationary night blindness with a negative ERG.

Original languageEnglish
Pages (from-to)1013-1020
Number of pages8
JournalArchives of Ophthalmology
Volume104
Issue number7
DOIs
Publication statusPublished - 07-1986
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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