Connection method of separated luminal regions of intestine from CT volumes

Masahiro Oda, Takayuki Kitasaka, Kazuhiro Furukawa, Osamu Watanabe, Takafumi Ando, Yoshiki Hirooka, Hidemi Goto, Kensaku Mori

Research output: Chapter in Book/Report/Conference proceedingConference contribution


This paper proposes a connection method of separated luminal regions of the intestine for Crohn's disease diagnosis. Crohn's disease is an inflammatory disease of the digestive tract. Capsule or conventional endoscopic diagnosis is performed for Crohn's disease diagnosis. However, parts of the intestines may not be observed in the endoscopic diagnosis if intestinal stenosis occurs. Endoscopes cannot pass through the stenosed parts. CT image-based diagnosis is developed as an alternative choice of the Crohn's disease. CT image-based diagnosis enables physicians to observe the entire intestines even if stenosed parts exist. CAD systems for Crohn's disease using CT volumes are recently developed. Such CAD systems need to reconstruct separated luminal regions of the intestines to analyze intestines. We propose a connection method of separated luminal regions of the intestines segmented from CT volumes. The luminal regions of the intestines are segmented from a CT volume. The centerlines of the luminal regions are calculated by using a thinning process. We enumerate all the possible sequences of the centerline segments. In this work, we newly introduce a condition using distance between connected ends points of the centerline segments. This condition eliminates unnatural connections of the centerline segments. Also, this condition reduces processing time. After generating a sequence list of the centerline segments, the correct sequence is obtained by using an evaluation function. We connect the luminal regions based on the correct sequence. Our experiments using four CT volumes showed that our method connected 6.5 out of 8.0 centerline segments per case. Processing times of the proposed method were reduced from the previous method.

Original languageEnglish
Title of host publicationMedical Imaging 2015
Subtitle of host publicationComputer-Aided Diagnosis
EditorsLubomir M. Hadjiiski, Lubomir M. Hadjiiski, Georgia D. Tourassi, Georgia D. Tourassi
ISBN (Electronic)9781628415049, 9781628415049
Publication statusPublished - 2015
Externally publishedYes
EventSPIE Medical Imaging Symposium 2015: Computer-Aided Diagnosis - Orlando, United States
Duration: 22-02-201525-02-2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherSPIE Medical Imaging Symposium 2015: Computer-Aided Diagnosis
Country/TerritoryUnited States

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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