Considerable Risk of Restenosis after Endoscopic Treatment for Hepaticojejunostomy Stricture after Living-Donor Liver Transplantation

Hideya Kamei, H. Imai, Y. Onishi, M. Ishihara, M. Nakamura, H. Kawashima, M. Ishigami, A. Ito, N. Ohmiya, Y. Hirooka, H. Goto, Y. Ogura

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Abstract

Background There are few reports on the short- and long-term follow-up of endoscopic retrograde cholangiography (ERC) in adult patients with hepaticojejunostomy (HJS) stricture after living-donor liver transplantation (LDLT). Methods Nine LDLT recipients underwent ERC with the use of double-balloon endoscopy (DBE) for HJS stricture at Nagoya University Hospital. We assessed the rate of reaching biliary anastomosis, procedure success rate, procedure duration, complications, improvement in liver function test results, and biliary anastomosis patency. Results In total, 19 ERC procedures with the use of DBE were performed for 9 adult LDLT recipients with HJS stricture from June 2006 to September 2014. Balloon dilation with the use of DBE was successfully performed in 5 of the 9 patients during the 1st procedure. Of the 4 patients in whom DBE-ERC failed to be completed, 3 patients underwent 2nd procedures successfully. Liver function test results were significantly improved in the successful cases. Four patients underwent 2nd DBE-ERC for stricture recurrence at a mean time of 2.3 years after the 1st successful procedure. Of those, 2 patients required 3rd procedures for stricture recurrence after the 2nd procedure. Conclusions DBE-ERC is promising as a treatment for HJS stricture in adult LDLT recipients in the short term. However, the DBE-ERC procedure may have a considerable risk of restenosis.

Original languageEnglish
Pages (from-to)2493-2498
Number of pages6
JournalTransplantation Proceedings
Volume47
Issue number8
DOIs
Publication statusPublished - 10-2015

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

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    Kamei, H., Imai, H., Onishi, Y., Ishihara, M., Nakamura, M., Kawashima, H., Ishigami, M., Ito, A., Ohmiya, N., Hirooka, Y., Goto, H., & Ogura, Y. (2015). Considerable Risk of Restenosis after Endoscopic Treatment for Hepaticojejunostomy Stricture after Living-Donor Liver Transplantation. Transplantation Proceedings, 47(8), 2493-2498. https://doi.org/10.1016/j.transproceed.2015.09.015