Consumption of fruits, vegetables, and seaweeds (sea vegetables) and pancreatic cancer risk: The Ohsaki Cohort Study

Michiko Shigihara, Taku Obara, Masato Nagai, Yumi Sugawara, Takashi Watanabe, Masako Kakizaki, Yoshikazu Nishino, Shinichi Kuriyama, Ichiro Tsuji

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Abstract

Studies on the effects of consumption of fruits, vegetables, and seaweeds on the incidence of pancreatic cancer are not conclusive. We examined the association (if any) between the consumption of fruits, vegetables, and seaweeds and the risk of pancreatic cancer in Japan. Data from 32,859 participants registered in the Ohsaki National Health Insurance Cohort Study who were 40-79 years old and free of cancer at baseline were analyzed. Consumption of fruits, vegetables, and seaweeds was assessed at baseline using a self-administered food frequency questionnaire (containing 40 items). Incidences of pancreatic cancer were identified by computer linkage with the Miyagi Prefectural Cancer Registry. During 11 years of follow-up, 137 pancreatic cancers (67 men and 70 women) were identified. The hazard ratios (95% confidence interval) of pancreatic cancer risk for the highest versus the lowest tertile were 0.82 (0.40-1.68, trend P= 0.57) in men and 0.64 (0.35-1.20, trend P= 0.22) in women for total consumption of fruits, 0.89 (0.46-1.73, trend P= 0.76) in men and 0.67 (0.33-1.35, trend P= 0.23) in women for total consumption of vegetables, and 0.92 (0.46-1.84, trend P= 0.81) in men for consumption of seaweeds (results for the consumption of seaweeds in women were not analyzed because of poor reliability), respectively. Total consumption of fruits, vegetables, and seaweeds was not associated with a reduced risk of pancreatic cancer.

Original languageEnglish
Pages (from-to)129-136
Number of pages8
JournalCancer Epidemiology
Volume38
Issue number2
DOIs
Publication statusPublished - 04-2014

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Oncology
  • Cancer Research

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    Shigihara, M., Obara, T., Nagai, M., Sugawara, Y., Watanabe, T., Kakizaki, M., Nishino, Y., Kuriyama, S., & Tsuji, I. (2014). Consumption of fruits, vegetables, and seaweeds (sea vegetables) and pancreatic cancer risk: The Ohsaki Cohort Study. Cancer Epidemiology, 38(2), 129-136. https://doi.org/10.1016/j.canep.2014.01.001