Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions

A pilot feasibility trial

Takafumi Omori, Yoshio Kamiya, Tomomitsu Tahara, Tomoyuki Shibata, Masakatsu Nakamura, Joh Yonemura, Masaaki Okubo, Daisuke Yoshioka, Takamitsu Ishizuka, Naoko Maruyama, Toshiaki Kamano, Hiroshi Fujita, Yoshihito Nakagawa, Mitsuo Nagasaka, Masami Iwata, Tomiyasu Arisawa, Ichiro Hirata

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background: Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.Methods: Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.Results: Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7%, specificity 97.4%), and dense vascular patterns (sensitivity 93.6%, specificity 91.6%), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97%, 100%, and 100%) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2%, specificity 97.0%).Conclusion: Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.

Original languageEnglish
Article number17
JournalBMC Gastroenterology
Volume12
DOIs
Publication statusPublished - 22-02-2012

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Narrow Band Imaging
Blood Vessels
Stomach
Polyps
Sensitivity and Specificity
Comb and Wattles
Neoplasms
Honey
Endoscopy

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Omori, Takafumi ; Kamiya, Yoshio ; Tahara, Tomomitsu ; Shibata, Tomoyuki ; Nakamura, Masakatsu ; Yonemura, Joh ; Okubo, Masaaki ; Yoshioka, Daisuke ; Ishizuka, Takamitsu ; Maruyama, Naoko ; Kamano, Toshiaki ; Fujita, Hiroshi ; Nakagawa, Yoshihito ; Nagasaka, Mitsuo ; Iwata, Masami ; Arisawa, Tomiyasu ; Hirata, Ichiro. / Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions : A pilot feasibility trial. In: BMC Gastroenterology. 2012 ; Vol. 12.
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abstract = "Background: Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.Methods: Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.Results: Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7{\%}, specificity 97.4{\%}), and dense vascular patterns (sensitivity 93.6{\%}, specificity 91.6{\%}), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97{\%}, 100{\%}, and 100{\%}) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2{\%}, specificity 97.0{\%}).Conclusion: Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.",
author = "Takafumi Omori and Yoshio Kamiya and Tomomitsu Tahara and Tomoyuki Shibata and Masakatsu Nakamura and Joh Yonemura and Masaaki Okubo and Daisuke Yoshioka and Takamitsu Ishizuka and Naoko Maruyama and Toshiaki Kamano and Hiroshi Fujita and Yoshihito Nakagawa and Mitsuo Nagasaka and Masami Iwata and Tomiyasu Arisawa and Ichiro Hirata",
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Omori, T, Kamiya, Y, Tahara, T, Shibata, T, Nakamura, M, Yonemura, J, Okubo, M, Yoshioka, D, Ishizuka, T, Maruyama, N, Kamano, T, Fujita, H, Nakagawa, Y, Nagasaka, M, Iwata, M, Arisawa, T & Hirata, I 2012, 'Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions: A pilot feasibility trial', BMC Gastroenterology, vol. 12, 17. https://doi.org/10.1186/1471-230X-12-17

Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions : A pilot feasibility trial. / Omori, Takafumi; Kamiya, Yoshio; Tahara, Tomomitsu; Shibata, Tomoyuki; Nakamura, Masakatsu; Yonemura, Joh; Okubo, Masaaki; Yoshioka, Daisuke; Ishizuka, Takamitsu; Maruyama, Naoko; Kamano, Toshiaki; Fujita, Hiroshi; Nakagawa, Yoshihito; Nagasaka, Mitsuo; Iwata, Masami; Arisawa, Tomiyasu; Hirata, Ichiro.

In: BMC Gastroenterology, Vol. 12, 17, 22.02.2012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions

T2 - A pilot feasibility trial

AU - Omori, Takafumi

AU - Kamiya, Yoshio

AU - Tahara, Tomomitsu

AU - Shibata, Tomoyuki

AU - Nakamura, Masakatsu

AU - Yonemura, Joh

AU - Okubo, Masaaki

AU - Yoshioka, Daisuke

AU - Ishizuka, Takamitsu

AU - Maruyama, Naoko

AU - Kamano, Toshiaki

AU - Fujita, Hiroshi

AU - Nakagawa, Yoshihito

AU - Nagasaka, Mitsuo

AU - Iwata, Masami

AU - Arisawa, Tomiyasu

AU - Hirata, Ichiro

PY - 2012/2/22

Y1 - 2012/2/22

N2 - Background: Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.Methods: Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.Results: Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7%, specificity 97.4%), and dense vascular patterns (sensitivity 93.6%, specificity 91.6%), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97%, 100%, and 100%) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2%, specificity 97.0%).Conclusion: Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.

AB - Background: Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.Methods: Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.Results: Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7%, specificity 97.4%), and dense vascular patterns (sensitivity 93.6%, specificity 91.6%), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97%, 100%, and 100%) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2%, specificity 97.0%).Conclusion: Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.

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U2 - 10.1186/1471-230X-12-17

DO - 10.1186/1471-230X-12-17

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JO - BMC Gastroenterology

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SN - 1471-230X

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