Correlations between geriatric nutritional risk index and peripheral artery disease in elderly coronary artery disease patients

Toshiki Kawamiya, Susumu Suzuki, Hideki Ishii, Kenshi Hirayama, Kazuhiro Harada, Yohei Shibata, Yosuke Tatami, Shingo Harata, Kazuhiro Kawashima, Ayako Kunimura, Yohei Takayama, Yusaku Shimbo, Naohiro Osugi, Dai Yamamoto, Tomoyuki Ota, Chikao Kono, Toyoaki Murohara

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Aim: Malnutrition is associated with the development of atherosclerosis and an increased risk of cardiovascular mortality in elderly patients. The present study aimed to investigate the association between the Geriatric Nutritional Risk Index (GNRI), a simple nutritional assessment tool, and the prevalence of peripheral artery disease (PAD) in elderly coronary artery disease patients. Methods: We evaluated 228 elderly coronary artery disease patients (mean age 74.0 ± 5.7 years). Ankle-brachial index (ABI) measurements were routinely carried out to investigate the prevalence of lower extremity PAD. Patients showing ABI <0.9 were defined as having PAD. Results: Based on our findings, 20.6% of the study patients had PAD. The median GNRI values were significantly lower in patients with PAD than those in patients without PAD (93.8 vs 100.0, P < 0.001). Even after multivariate adjustment, GNRI values were independently associated with PAD (odds ratio 0.94; 95% confidence interval 0.89–0.99; P = 0.024). Furthermore, patients with low GNRI and high C-reactive protein levels had a 5.5-fold higher risk of having PAD than those with high GNRI and low C-reactive protein levels. Conclusions: GNRI values showed a strong relationship with PAD in elderly coronary artery disease patients. These data reinforce the utility of GNRI as a screening tool in clinical practice. Geriatr Gerontol Int 2017; 17: 1057–1062.

Original languageEnglish
Pages (from-to)1057-1062
Number of pages6
JournalGeriatrics and Gerontology International
Volume17
Issue number7
DOIs
Publication statusPublished - 07-2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

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