TY - JOUR
T1 - Cortical dysfunction of the supplementary motor area in a spasmodic dysphonia patient
AU - Hirano, Shigeru
AU - Kojima, Hisayoshi
AU - Naito, Yasushi
AU - Tateya, Ichiro
AU - Shoji, Kazuhiko
AU - Kaneko, Ken Ichi
AU - Inoue, Masato
AU - Nishizawa, Sadahiko
AU - Konishi, Junji
N1 - Funding Information:
Supported by a grant for research on eye and ear sciences, immunology, allergy and organ transplantation from the Ministry of Health and Welfare, and by Grants-in-Aid for scientific research (B)11470356 from the Ministry of Education, Science, Sports and Culture in Japan.
PY - 2001/5
Y1 - 2001/5
N2 - The etiology of spasmodic dysphonia (SD) is still unknown. In the present study, cortical function of a 59-year-old male patient with adductor type SD was examined during phonation with positron emission tomography (PET). Magnetic resonance imaging showed no organic abnormality in the brain. However, PET showed remarkable activities during phonation in the left motor cortex, Broca's area, the cerebellum, and the auditory cortices, whereas the supplementary motor area (SMA) was not activated. The SMA is known to function for motor planning and programming and is usually activated in normal phonation. Several previous reports have shown that the damage of the SMA caused a severe disturbance of voluntary vocalization. In the present case, it was suggested that the functional deficit of the SMA might be related to SD.
AB - The etiology of spasmodic dysphonia (SD) is still unknown. In the present study, cortical function of a 59-year-old male patient with adductor type SD was examined during phonation with positron emission tomography (PET). Magnetic resonance imaging showed no organic abnormality in the brain. However, PET showed remarkable activities during phonation in the left motor cortex, Broca's area, the cerebellum, and the auditory cortices, whereas the supplementary motor area (SMA) was not activated. The SMA is known to function for motor planning and programming and is usually activated in normal phonation. Several previous reports have shown that the damage of the SMA caused a severe disturbance of voluntary vocalization. In the present case, it was suggested that the functional deficit of the SMA might be related to SD.
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U2 - 10.1053/ajot.2001.23436
DO - 10.1053/ajot.2001.23436
M3 - Article
C2 - 11351294
AN - SCOPUS:0035340410
SN - 0196-0709
VL - 22
SP - 219
EP - 222
JO - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
JF - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
IS - 3
ER -