TY - JOUR
T1 - Current management of Staphylococcus aureus bacteremia in a Japanese university hospital
AU - Hanai, Shogo
AU - Yokose, Masashi
AU - Harada, Yukinori
AU - Doi, Yohei
AU - Shimizu, Taro
N1 - Publisher Copyright:
© 2024 Shogo Hanai, MD et al.
PY - 2024
Y1 - 2024
N2 - Objectives: Consultation with infectious disease specialists is associated with reduced patient mortality in the care of patients with Staphylococcus aureus bacteremia (SAB) through appropriate management of complications including infective endocarditis. This study aimed to determine the rates of confirmation of a negative blood culture, implementation of echocardiography, and administration of appropriate antibiotics in patients with SAB at a university hospital in Japan that provides general internal medicine and not an infectious disease consultation service. Methods: We conducted a retrospective cohort study at Dokkyo Medical University Hospital in Japan. Patients eligible for inclusion in the study were ≥20 years of age with ≥1 positive blood culture for S. aureus identified in a clinical microbiology laboratory. The primary outcome was the proportion of patients with confirmation of a negative blood culture, implementation of echocardiography, and administration of appropriate antimicrobial agents. Results: A total of 109 patients with SAB were included in the analysis. Follow-up blood cultures were collected in 91 patients and negative results were documented in 88 patients. Follow-up blood culture collection was performed within 4 days of the initial blood culture collection in 49 patients. Echocardiography was performed appropriately in 40 patients. Appropriate antibiotic therapy was administered in 36 patients. Conclusions: Quality-of-care indicators were more commonly implemented in patients with SAB who received general internal medicine consultation than in those who did not.
AB - Objectives: Consultation with infectious disease specialists is associated with reduced patient mortality in the care of patients with Staphylococcus aureus bacteremia (SAB) through appropriate management of complications including infective endocarditis. This study aimed to determine the rates of confirmation of a negative blood culture, implementation of echocardiography, and administration of appropriate antibiotics in patients with SAB at a university hospital in Japan that provides general internal medicine and not an infectious disease consultation service. Methods: We conducted a retrospective cohort study at Dokkyo Medical University Hospital in Japan. Patients eligible for inclusion in the study were ≥20 years of age with ≥1 positive blood culture for S. aureus identified in a clinical microbiology laboratory. The primary outcome was the proportion of patients with confirmation of a negative blood culture, implementation of echocardiography, and administration of appropriate antimicrobial agents. Results: A total of 109 patients with SAB were included in the analysis. Follow-up blood cultures were collected in 91 patients and negative results were documented in 88 patients. Follow-up blood culture collection was performed within 4 days of the initial blood culture collection in 49 patients. Echocardiography was performed appropriately in 40 patients. Appropriate antibiotic therapy was administered in 36 patients. Conclusions: Quality-of-care indicators were more commonly implemented in patients with SAB who received general internal medicine consultation than in those who did not.
KW - Echocardiography
KW - General internal medicine
KW - Management
KW - Staphylococcus aureus bacteremia
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U2 - 10.20407/fmj.2024-010
DO - 10.20407/fmj.2024-010
M3 - Article
AN - SCOPUS:85208991021
SN - 2189-7247
VL - 10
SP - 106
EP - 110
JO - Fujita Medical Journal
JF - Fujita Medical Journal
IS - 4
ER -