Cutaneous Malassezia microbiota in atopic dermatitis patients differ by gender and body part

Narifumi Akaza, Hirohiko Akamatsu, Yasuyuki Sasaki, Shiori Takeoka, Masataka Kishi, Hiroshi Mizutani, Akiyo Sano, Keiko Hirokawa, Satoru Nakata, Kayoko Matsunaga

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Background:Malassezia is a particularly important factor in the occurrence of atopic dermatitis (AD).Aim: The aim of this study was to quantitatively clarify the Malassezia species isolated from AD patients by gender, body part and analytical method in detail. Methods: The subjects were 20 AD males and 47 AD females. Samples were collected from lesion and nonlesion areas on the face and upper trunk of AD patients. Malassezia DNA was analyzed using a real-time PCR system. Results: The cutaneous Malassezia microbiota in AD patients differed by gender, body part and analytical method. Conclusions: The present results indicate the possibility that the influence of Malassezia antigens is different according to gender and body part.

Original languageEnglish
Pages (from-to)253-260
Number of pages8
JournalDermatology
Volume221
Issue number3
DOIs
Publication statusPublished - 01-10-2010

All Science Journal Classification (ASJC) codes

  • Dermatology

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