Data describing the effects of depletion of Myoparr, myogenin, Ddx17, and hnRNPK in differentiating C2C12 cells

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Abstract

Myoparr is a promoter-associated long non-coding RNA (lncRNA) that is expressed from the promoter region of myogenin gene. Myoparr is essential for the proper differentiation of skeletal muscle cells; it accomplishes this by activating the expression of myogenin and myogenic microRNAs (miRNAs). In this study, we provide the RNA-seq data describing the changes in gene expression induced by knockdown of Myoparr, myogenin, and two Myoparr-binding proteins (Ddx17 and hnRNPK) during skeletal muscle differentiation in C2C12 cells. Raw data files were deposited in Sequence Read Archive in DNA Data Bank of Japan (DDBJ) under the accession number DRA005527. These data are related to the research article “Myogenin promoter-associated lncRNA Myoparr is essential for myogenic differentiation” Hitachi et al., 2019.

Original languageEnglish
Article number104172
JournalData in Brief
Volume25
DOIs
Publication statusPublished - 01-08-2019

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Myogenin
Long Noncoding RNA
Skeletal Muscle
Information Storage and Retrieval
Nucleic Acid Databases
MicroRNAs
Genetic Promoter Regions
Muscle Cells
Carrier Proteins
RNA
Gene Expression
Research
Genes

All Science Journal Classification (ASJC) codes

  • General

Cite this

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title = "Data describing the effects of depletion of Myoparr, myogenin, Ddx17, and hnRNPK in differentiating C2C12 cells",
abstract = "Myoparr is a promoter-associated long non-coding RNA (lncRNA) that is expressed from the promoter region of myogenin gene. Myoparr is essential for the proper differentiation of skeletal muscle cells; it accomplishes this by activating the expression of myogenin and myogenic microRNAs (miRNAs). In this study, we provide the RNA-seq data describing the changes in gene expression induced by knockdown of Myoparr, myogenin, and two Myoparr-binding proteins (Ddx17 and hnRNPK) during skeletal muscle differentiation in C2C12 cells. Raw data files were deposited in Sequence Read Archive in DNA Data Bank of Japan (DDBJ) under the accession number DRA005527. These data are related to the research article “Myogenin promoter-associated lncRNA Myoparr is essential for myogenic differentiation” Hitachi et al., 2019.",
author = "Keisuke Hitachi and Kunihiro Tsuchida",
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AU - Hitachi, Keisuke

AU - Tsuchida, Kunihiro

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