Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster

Kayoko Suzuki, Tetsushi Yoshikawa, Akiko Yagami, Kayoko Matsunaga, Yoshizo Asano

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

We examined the excretion of varicella zoster virus (VZV) in hospitalized patients with herpes zoster localized to the thoracic region whose skin lesions were covered with either hydrocolloid dressing agents (hydrocolloid group) or conventional gauze bandages (gauze group). The presence of VZV DNA in swab samples from lesion coverings, the throat, and filters of air purifiers was examined by use of a sensitive polymerase chain reaction assay. For the hydrocolloid group, VZV was detected in none of the samples from lesion coverings or air purifier filters; for the gauze group, VZV DNA was detected in samples from gauze coverings and air purifier filters for all 6 patients. VZV DNA was detected less frequently in throat samples from patients in the hydrocolloid group than in those from patients in the gauze group. The results of the present study suggest that hydrocolloid dressing agents prevent excretion of aerosolized VZV DNA from skin lesions of patients with localized herpes zoster.

Original languageEnglish
Pages (from-to)1009-1012
Number of pages4
JournalJournal of Infectious Diseases
Volume189
Issue number6
DOIs
Publication statusPublished - 15-03-2004

Fingerprint

Air Filters
Human Herpesvirus 3
Herpes Zoster
DNA
Colloids
Hydrocolloid Bandages
Pharynx
Skin
Bandages
Thorax
Polymerase Chain Reaction

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Infectious Diseases

Cite this

@article{fa773c1a393045f9a0b465ef417dc696,
title = "Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster",
abstract = "We examined the excretion of varicella zoster virus (VZV) in hospitalized patients with herpes zoster localized to the thoracic region whose skin lesions were covered with either hydrocolloid dressing agents (hydrocolloid group) or conventional gauze bandages (gauze group). The presence of VZV DNA in swab samples from lesion coverings, the throat, and filters of air purifiers was examined by use of a sensitive polymerase chain reaction assay. For the hydrocolloid group, VZV was detected in none of the samples from lesion coverings or air purifier filters; for the gauze group, VZV DNA was detected in samples from gauze coverings and air purifier filters for all 6 patients. VZV DNA was detected less frequently in throat samples from patients in the hydrocolloid group than in those from patients in the gauze group. The results of the present study suggest that hydrocolloid dressing agents prevent excretion of aerosolized VZV DNA from skin lesions of patients with localized herpes zoster.",
author = "Kayoko Suzuki and Tetsushi Yoshikawa and Akiko Yagami and Kayoko Matsunaga and Yoshizo Asano",
year = "2004",
month = "3",
day = "15",
doi = "10.1086/382029",
language = "English",
volume = "189",
pages = "1009--1012",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "6",

}

Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster. / Suzuki, Kayoko; Yoshikawa, Tetsushi; Yagami, Akiko; Matsunaga, Kayoko; Asano, Yoshizo.

In: Journal of Infectious Diseases, Vol. 189, No. 6, 15.03.2004, p. 1009-1012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster

AU - Suzuki, Kayoko

AU - Yoshikawa, Tetsushi

AU - Yagami, Akiko

AU - Matsunaga, Kayoko

AU - Asano, Yoshizo

PY - 2004/3/15

Y1 - 2004/3/15

N2 - We examined the excretion of varicella zoster virus (VZV) in hospitalized patients with herpes zoster localized to the thoracic region whose skin lesions were covered with either hydrocolloid dressing agents (hydrocolloid group) or conventional gauze bandages (gauze group). The presence of VZV DNA in swab samples from lesion coverings, the throat, and filters of air purifiers was examined by use of a sensitive polymerase chain reaction assay. For the hydrocolloid group, VZV was detected in none of the samples from lesion coverings or air purifier filters; for the gauze group, VZV DNA was detected in samples from gauze coverings and air purifier filters for all 6 patients. VZV DNA was detected less frequently in throat samples from patients in the hydrocolloid group than in those from patients in the gauze group. The results of the present study suggest that hydrocolloid dressing agents prevent excretion of aerosolized VZV DNA from skin lesions of patients with localized herpes zoster.

AB - We examined the excretion of varicella zoster virus (VZV) in hospitalized patients with herpes zoster localized to the thoracic region whose skin lesions were covered with either hydrocolloid dressing agents (hydrocolloid group) or conventional gauze bandages (gauze group). The presence of VZV DNA in swab samples from lesion coverings, the throat, and filters of air purifiers was examined by use of a sensitive polymerase chain reaction assay. For the hydrocolloid group, VZV was detected in none of the samples from lesion coverings or air purifier filters; for the gauze group, VZV DNA was detected in samples from gauze coverings and air purifier filters for all 6 patients. VZV DNA was detected less frequently in throat samples from patients in the hydrocolloid group than in those from patients in the gauze group. The results of the present study suggest that hydrocolloid dressing agents prevent excretion of aerosolized VZV DNA from skin lesions of patients with localized herpes zoster.

UR - http://www.scopus.com/inward/record.url?scp=1642284389&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1642284389&partnerID=8YFLogxK

U2 - 10.1086/382029

DO - 10.1086/382029

M3 - Article

VL - 189

SP - 1009

EP - 1012

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 6

ER -