TY - JOUR
T1 - Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster
AU - Suzuki, Kayoko
AU - Yoshikawa, Tetsushi
AU - Tomitaka, Akiko
AU - Matsunaga, Kayoko
AU - Asano, Yoshizo
N1 - Funding Information:
Received 11 April 2003; accepted 15 September 2003; electronically published 27 February 2004. Financial support: Fujita Health University; Ministry of Education, Culture, Sports, Science, and Technology of Japan (grant-in-aid for scientific research and for open research to Center of Fujita Health University). Reprints or correspondence: Dr. Kayoko Suzuki, Dept. of Dermatology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192 Japan ([email protected]).
PY - 2004/3/15
Y1 - 2004/3/15
N2 - We examined the excretion of varicella zoster virus (VZV) in hospitalized patients with herpes zoster localized to the thoracic region whose skin lesions were covered with either hydrocolloid dressing agents (hydrocolloid group) or conventional gauze bandages (gauze group). The presence of VZV DNA in swab samples from lesion coverings, the throat, and filters of air purifiers was examined by use of a sensitive polymerase chain reaction assay. For the hydrocolloid group, VZV was detected in none of the samples from lesion coverings or air purifier filters; for the gauze group, VZV DNA was detected in samples from gauze coverings and air purifier filters for all 6 patients. VZV DNA was detected less frequently in throat samples from patients in the hydrocolloid group than in those from patients in the gauze group. The results of the present study suggest that hydrocolloid dressing agents prevent excretion of aerosolized VZV DNA from skin lesions of patients with localized herpes zoster.
AB - We examined the excretion of varicella zoster virus (VZV) in hospitalized patients with herpes zoster localized to the thoracic region whose skin lesions were covered with either hydrocolloid dressing agents (hydrocolloid group) or conventional gauze bandages (gauze group). The presence of VZV DNA in swab samples from lesion coverings, the throat, and filters of air purifiers was examined by use of a sensitive polymerase chain reaction assay. For the hydrocolloid group, VZV was detected in none of the samples from lesion coverings or air purifier filters; for the gauze group, VZV DNA was detected in samples from gauze coverings and air purifier filters for all 6 patients. VZV DNA was detected less frequently in throat samples from patients in the hydrocolloid group than in those from patients in the gauze group. The results of the present study suggest that hydrocolloid dressing agents prevent excretion of aerosolized VZV DNA from skin lesions of patients with localized herpes zoster.
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U2 - 10.1086/382029
DO - 10.1086/382029
M3 - Article
C2 - 14999603
AN - SCOPUS:1642284389
SN - 0022-1899
VL - 189
SP - 1009
EP - 1012
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 6
ER -
