Detection of DNA of six human herpesviruses in the cerebrospinal fluid of immunocompetent non-herpetic acute limbic encephalitis patients

Tetsushi Yoshikawa, Yoshizo Asano, Yukitoshi Takahashi

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Abstract

In order to determine whether six other human herpesviruses, aside from herpes simplex virus, are associated with non-herpetic acute limbic encephalitis in immunocompetent individuals, real-time PCR was used to detect the DNA of herpesviruses in CSF collected from 61 patients with this form of encephalitis. Five of the human herpesviruses tested were not detected in any of the 61 CSF samples. EBV DNA was detected in one CSF sample. The EBV DNA-positive patient was a 36-year-old woman who presented with fever, headache, mild somnolence, and the typical neuroimaging findings.

Original languageEnglish
Pages (from-to)471-474
Number of pages4
JournalMICROBIOLOGY and IMMUNOLOGY
Volume54
Issue number8
DOIs
Publication statusPublished - 08-2010

Fingerprint

Limbic Encephalitis
Herpesviridae
Cerebrospinal Fluid
Human Herpesvirus 4
DNA
Encephalitis
Simplexvirus
Neuroimaging
Headache
Real-Time Polymerase Chain Reaction
Fever

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Virology

Cite this

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title = "Detection of DNA of six human herpesviruses in the cerebrospinal fluid of immunocompetent non-herpetic acute limbic encephalitis patients",
abstract = "In order to determine whether six other human herpesviruses, aside from herpes simplex virus, are associated with non-herpetic acute limbic encephalitis in immunocompetent individuals, real-time PCR was used to detect the DNA of herpesviruses in CSF collected from 61 patients with this form of encephalitis. Five of the human herpesviruses tested were not detected in any of the 61 CSF samples. EBV DNA was detected in one CSF sample. The EBV DNA-positive patient was a 36-year-old woman who presented with fever, headache, mild somnolence, and the typical neuroimaging findings.",
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Detection of DNA of six human herpesviruses in the cerebrospinal fluid of immunocompetent non-herpetic acute limbic encephalitis patients. / Yoshikawa, Tetsushi; Asano, Yoshizo; Takahashi, Yukitoshi.

In: MICROBIOLOGY and IMMUNOLOGY, Vol. 54, No. 8, 08.2010, p. 471-474.

Research output: Contribution to journalComment/debate

TY - JOUR

T1 - Detection of DNA of six human herpesviruses in the cerebrospinal fluid of immunocompetent non-herpetic acute limbic encephalitis patients

AU - Yoshikawa, Tetsushi

AU - Asano, Yoshizo

AU - Takahashi, Yukitoshi

PY - 2010/8

Y1 - 2010/8

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AB - In order to determine whether six other human herpesviruses, aside from herpes simplex virus, are associated with non-herpetic acute limbic encephalitis in immunocompetent individuals, real-time PCR was used to detect the DNA of herpesviruses in CSF collected from 61 patients with this form of encephalitis. Five of the human herpesviruses tested were not detected in any of the 61 CSF samples. EBV DNA was detected in one CSF sample. The EBV DNA-positive patient was a 36-year-old woman who presented with fever, headache, mild somnolence, and the typical neuroimaging findings.

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JO - Microbiology and Immunology

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