Development and initial testing of a permanently implantable centrifugal pump

Tadashi Nakazawa, Yoshiyuki Takami, Robert Benkowski, Satoshi Ohtsubo, Ohashi Yukio, Eiki Tayama, Goro Ohtsuka, Yoshinari Niimi, Julie Glueck, Akinori Sueoka, Helmut Schmallegger, Heinrich Schima, Ernst Wolner, Yukihiko Nosé

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

To be able to salvage heart failure patients, the need for an economical permanent ventricular assist device is increasing. To meet this increasing demand, a miniaturized centrifugal blood pump has been developed as a permanently implantable device. The Gyro permanently implantable model (PI- 601) incorporates a sealless design with a blood stagnation free structure. The pump impeller is magnetically coupled to the driver magnet in a sealless manner. This pump is atraumatic and antithrombogenic and incorporates a double pivot bearing system. A miniaturized actuator was utilized in this system in collaboration with the University of Vienna. The priming volume of this pump is 20 ml. The overall size of the pump actuator package is 53 mm in height and 65 mm in diameter, 145 ml of displacement volume, and 305 g in weight. Testing to date has included in vitro hydraulic performance and hemolysis. This pump can provide 5 L/min against a 110 mm Hg total pressure head at 2,000 rpm and 8 L/min against 150 mm Hg at 2,500 rpm. The normalized index of hemolysis (NIH) value of this pump was 0.0028 g/100 L at 5 L/min against 100 mm Hg. A preliminary anatomical study revealed the possibility of the implantability of 2 such systems in biventricular bypass at a preperitoneal location. This system is feasible for use as a permanently implantable biventricular assist device.

Original languageEnglish
Pages (from-to)597-601
Number of pages5
JournalArtificial Organs
Volume21
Issue number7
DOIs
Publication statusPublished - 01-01-1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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