Development of a simple screening test for sarcopenia in older adults

Shinya Ishii, Tomoki Tanaka, Koji Shibasaki, Yasuyoshi Ouchi, Takeshi Kikutani, Takashi Higashiguchi, Shuichi P. Obuchi, Kazuko Ishikawa-Takata, Hirohiko Hirano, Hisashi Kawai, Tetsuo Tsuji, Katsuya Iijima

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Aim: To develop a simple screening test to identify older adults at high risk for sarcopenia. Methods: We studied 1971 functionally independent, community-dwelling adults aged 65 years or older randomly selected from the resident register of Kashiwa city, Chiba, Japan. Data collection was carried out between September and November 2012. Sarcopenia was defined based on low muscle mass measured by bioimpedance analysis and either low muscle strength characterized by handgrip or low physical performance characterized by slow gait speed. Results: The prevalence of sarcopenia was 14.2% in men and 22.1% in women. After the variable selection procedure, the final model to estimate the probability of sarcopenia included three variables: age, grip strength and calf circumference. The area under the receiver operating characteristic curve, a measure of discrimination, of the final model was 0.939 with 95% confidence interval (CI) of 0.918-0.958 for men, and 0.909 with 95% CI of 0.887-0.931 for women. We created a score chart for each sex based on the final model. When the sum of sensitivity and specificity was maximized, sensitivity, specificity, and positive and negative predictive values for sarcopenia were 84.9%, 88.2%, 54.4%, and 97.2% for men, 75.5%, 92.0%, 72.8%, and 93.0% for women, respectively. Conclusions: The presence of sarcopenia could be detected using three easily obtainable variables with high accuracy. The screening test we developed could help identify functionally independent older adults with sarcopenia who are good candidates for intervention.

Original languageEnglish
Pages (from-to)93-101
Number of pages9
JournalGeriatrics and Gerontology International
Volume14
Issue numberSUPPL.1
DOIs
Publication statusPublished - 01-02-2014

Fingerprint

Sarcopenia
confidence
selection procedure
discrimination
candidacy
recipient
Japan
resident
Confidence Intervals
Independent Living
Sensitivity and Specificity
Muscle Strength
Hand Strength
community
performance
ROC Curve
Muscles

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

Cite this

Ishii, S., Tanaka, T., Shibasaki, K., Ouchi, Y., Kikutani, T., Higashiguchi, T., ... Iijima, K. (2014). Development of a simple screening test for sarcopenia in older adults. Geriatrics and Gerontology International, 14(SUPPL.1), 93-101. https://doi.org/10.1111/ggi.12197
Ishii, Shinya ; Tanaka, Tomoki ; Shibasaki, Koji ; Ouchi, Yasuyoshi ; Kikutani, Takeshi ; Higashiguchi, Takashi ; Obuchi, Shuichi P. ; Ishikawa-Takata, Kazuko ; Hirano, Hirohiko ; Kawai, Hisashi ; Tsuji, Tetsuo ; Iijima, Katsuya. / Development of a simple screening test for sarcopenia in older adults. In: Geriatrics and Gerontology International. 2014 ; Vol. 14, No. SUPPL.1. pp. 93-101.
@article{9f069957df374cb38f9792c0faad1f9c,
title = "Development of a simple screening test for sarcopenia in older adults",
abstract = "Aim: To develop a simple screening test to identify older adults at high risk for sarcopenia. Methods: We studied 1971 functionally independent, community-dwelling adults aged 65 years or older randomly selected from the resident register of Kashiwa city, Chiba, Japan. Data collection was carried out between September and November 2012. Sarcopenia was defined based on low muscle mass measured by bioimpedance analysis and either low muscle strength characterized by handgrip or low physical performance characterized by slow gait speed. Results: The prevalence of sarcopenia was 14.2{\%} in men and 22.1{\%} in women. After the variable selection procedure, the final model to estimate the probability of sarcopenia included three variables: age, grip strength and calf circumference. The area under the receiver operating characteristic curve, a measure of discrimination, of the final model was 0.939 with 95{\%} confidence interval (CI) of 0.918-0.958 for men, and 0.909 with 95{\%} CI of 0.887-0.931 for women. We created a score chart for each sex based on the final model. When the sum of sensitivity and specificity was maximized, sensitivity, specificity, and positive and negative predictive values for sarcopenia were 84.9{\%}, 88.2{\%}, 54.4{\%}, and 97.2{\%} for men, 75.5{\%}, 92.0{\%}, 72.8{\%}, and 93.0{\%} for women, respectively. Conclusions: The presence of sarcopenia could be detected using three easily obtainable variables with high accuracy. The screening test we developed could help identify functionally independent older adults with sarcopenia who are good candidates for intervention.",
author = "Shinya Ishii and Tomoki Tanaka and Koji Shibasaki and Yasuyoshi Ouchi and Takeshi Kikutani and Takashi Higashiguchi and Obuchi, {Shuichi P.} and Kazuko Ishikawa-Takata and Hirohiko Hirano and Hisashi Kawai and Tetsuo Tsuji and Katsuya Iijima",
year = "2014",
month = "2",
day = "1",
doi = "10.1111/ggi.12197",
language = "English",
volume = "14",
pages = "93--101",
journal = "Geriatrics and Gerontology International",
issn = "1444-1586",
publisher = "Japan Geriatrics Society",
number = "SUPPL.1",

}

Ishii, S, Tanaka, T, Shibasaki, K, Ouchi, Y, Kikutani, T, Higashiguchi, T, Obuchi, SP, Ishikawa-Takata, K, Hirano, H, Kawai, H, Tsuji, T & Iijima, K 2014, 'Development of a simple screening test for sarcopenia in older adults', Geriatrics and Gerontology International, vol. 14, no. SUPPL.1, pp. 93-101. https://doi.org/10.1111/ggi.12197

Development of a simple screening test for sarcopenia in older adults. / Ishii, Shinya; Tanaka, Tomoki; Shibasaki, Koji; Ouchi, Yasuyoshi; Kikutani, Takeshi; Higashiguchi, Takashi; Obuchi, Shuichi P.; Ishikawa-Takata, Kazuko; Hirano, Hirohiko; Kawai, Hisashi; Tsuji, Tetsuo; Iijima, Katsuya.

In: Geriatrics and Gerontology International, Vol. 14, No. SUPPL.1, 01.02.2014, p. 93-101.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Development of a simple screening test for sarcopenia in older adults

AU - Ishii, Shinya

AU - Tanaka, Tomoki

AU - Shibasaki, Koji

AU - Ouchi, Yasuyoshi

AU - Kikutani, Takeshi

AU - Higashiguchi, Takashi

AU - Obuchi, Shuichi P.

AU - Ishikawa-Takata, Kazuko

AU - Hirano, Hirohiko

AU - Kawai, Hisashi

AU - Tsuji, Tetsuo

AU - Iijima, Katsuya

PY - 2014/2/1

Y1 - 2014/2/1

N2 - Aim: To develop a simple screening test to identify older adults at high risk for sarcopenia. Methods: We studied 1971 functionally independent, community-dwelling adults aged 65 years or older randomly selected from the resident register of Kashiwa city, Chiba, Japan. Data collection was carried out between September and November 2012. Sarcopenia was defined based on low muscle mass measured by bioimpedance analysis and either low muscle strength characterized by handgrip or low physical performance characterized by slow gait speed. Results: The prevalence of sarcopenia was 14.2% in men and 22.1% in women. After the variable selection procedure, the final model to estimate the probability of sarcopenia included three variables: age, grip strength and calf circumference. The area under the receiver operating characteristic curve, a measure of discrimination, of the final model was 0.939 with 95% confidence interval (CI) of 0.918-0.958 for men, and 0.909 with 95% CI of 0.887-0.931 for women. We created a score chart for each sex based on the final model. When the sum of sensitivity and specificity was maximized, sensitivity, specificity, and positive and negative predictive values for sarcopenia were 84.9%, 88.2%, 54.4%, and 97.2% for men, 75.5%, 92.0%, 72.8%, and 93.0% for women, respectively. Conclusions: The presence of sarcopenia could be detected using three easily obtainable variables with high accuracy. The screening test we developed could help identify functionally independent older adults with sarcopenia who are good candidates for intervention.

AB - Aim: To develop a simple screening test to identify older adults at high risk for sarcopenia. Methods: We studied 1971 functionally independent, community-dwelling adults aged 65 years or older randomly selected from the resident register of Kashiwa city, Chiba, Japan. Data collection was carried out between September and November 2012. Sarcopenia was defined based on low muscle mass measured by bioimpedance analysis and either low muscle strength characterized by handgrip or low physical performance characterized by slow gait speed. Results: The prevalence of sarcopenia was 14.2% in men and 22.1% in women. After the variable selection procedure, the final model to estimate the probability of sarcopenia included three variables: age, grip strength and calf circumference. The area under the receiver operating characteristic curve, a measure of discrimination, of the final model was 0.939 with 95% confidence interval (CI) of 0.918-0.958 for men, and 0.909 with 95% CI of 0.887-0.931 for women. We created a score chart for each sex based on the final model. When the sum of sensitivity and specificity was maximized, sensitivity, specificity, and positive and negative predictive values for sarcopenia were 84.9%, 88.2%, 54.4%, and 97.2% for men, 75.5%, 92.0%, 72.8%, and 93.0% for women, respectively. Conclusions: The presence of sarcopenia could be detected using three easily obtainable variables with high accuracy. The screening test we developed could help identify functionally independent older adults with sarcopenia who are good candidates for intervention.

UR - http://www.scopus.com/inward/record.url?scp=84892860023&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892860023&partnerID=8YFLogxK

U2 - 10.1111/ggi.12197

DO - 10.1111/ggi.12197

M3 - Article

VL - 14

SP - 93

EP - 101

JO - Geriatrics and Gerontology International

JF - Geriatrics and Gerontology International

SN - 1444-1586

IS - SUPPL.1

ER -