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Development of an Automated Dip-Type ELISA System

  • Toshihiro Kasama
  • , Marie Shinohara
  • , Yukiko T. Matsunaga
  • , Ryo Miyake

Research output: Contribution to journalArticlepeer-review

Abstract

This study introduces an automated enzyme-linked immunosorbent assay (ELISA) system employing a novel dip methodology. Unlike traditional ELISA, which requires complex liquid handling, this approach keeps samples and reagents stationary while immersing antibody-coated reaction fields sequentially. This design eliminates pumps and tubing, reducing maintenance, reagent waste, and overall costs. The system, controlled via a microcontroller and web-based interface, demonstrated accurate and efficient C-reactive protein analysis in human serum. With reduced reagent volumes, lower operational costs, and simplified handling, this system offers significant potential for point-of-care testing, telemedicine, and broader next-generation healthcare applications.

Original languageEnglish
Pages (from-to)41-45
Number of pages5
JournalElectronics and Communications in Japan
Volume108
Issue number4
DOIs
Publication statusPublished - 12-2025
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • General Physics and Astronomy
  • Computer Networks and Communications
  • Electrical and Electronic Engineering
  • Applied Mathematics

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