Diagnosis of the invasion depth of gastric cancer using MDCT with virtual gastroscopy

Comparison with staging with endoscopic ultrasound

Kazuhiro Furukawa, Ryoji Miyahara, Akihiro Itoh, Naoki Omiya, Yoshiki Hirooka, Kensaku Mori, Hidemi Goto

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

OBJECTIVE. The objectives of this study were to retrospectively evaluate the lesion detection rate of gastric cancer using only virtual gastroscopy generated from MDCT images and the accuracy of invasion depth diagnosis (T staging) using virtual gastroscopy together with contrast-enhanced MDCT with multiplanar reconstruction (MPR) images (virtual gastroscopy with MPR), and to compare the diagnostic performance between virtual gastroscopy with MPR images and endoscopic ultrasound. MATERIALS AND METHODS. The subjects consisted of 175 patients with a total of 186 endoscopically proven gastric cancer lesions. All patients underwent dynamic MDCT (arterial and venous phase) for preoperative staging and underwent surgery or endoscopic treatment. In 129 patients (135 lesions) who were also examined using endoscopic ultrasound, the T staging accuracy was also compared between the two modalities. Two endoscopists independently evaluated the lesion detection rate on virtual gastroscopy images alone and determined the T stage on virtual gastroscopy with MPR images. The T staging included the ability to differentiate T1a from T1b lesions. RESULTS. The overall lesion detection rate was 67.7% (126/186). The detection rates of T1a, T1b, and T2 or deeper were 37.8% (28/74), 75.0% (39/52), and 98.3% (59/60), respectively, showing statistically significant differences (p < 0.001). The T staging accuracies were 82.2% (111/135) using virtual gastroscopy with MPR images and 83.7% (113/135) using endoscopic ultrasound, showing no statistically significant difference (p = 0.850). The main causes of over- and understaging were an ulcer or ulcer scar and poorly differentiated adenocarcinomas, non-solid type, respectively. CONCLUSION. Virtual gastroscopy with MPR imaging is a useful modality in the T staging of gastric cancer.

Original languageEnglish
Pages (from-to)867-875
Number of pages9
JournalAmerican Journal of Roentgenology
Volume197
Issue number4
DOIs
Publication statusPublished - 01-10-2011
Externally publishedYes

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Gastroscopy
Stomach Neoplasms
Computer-Assisted Image Processing
Ulcer
Cicatrix
Adenocarcinoma

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Furukawa, Kazuhiro ; Miyahara, Ryoji ; Itoh, Akihiro ; Omiya, Naoki ; Hirooka, Yoshiki ; Mori, Kensaku ; Goto, Hidemi. / Diagnosis of the invasion depth of gastric cancer using MDCT with virtual gastroscopy : Comparison with staging with endoscopic ultrasound. In: American Journal of Roentgenology. 2011 ; Vol. 197, No. 4. pp. 867-875.
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abstract = "OBJECTIVE. The objectives of this study were to retrospectively evaluate the lesion detection rate of gastric cancer using only virtual gastroscopy generated from MDCT images and the accuracy of invasion depth diagnosis (T staging) using virtual gastroscopy together with contrast-enhanced MDCT with multiplanar reconstruction (MPR) images (virtual gastroscopy with MPR), and to compare the diagnostic performance between virtual gastroscopy with MPR images and endoscopic ultrasound. MATERIALS AND METHODS. The subjects consisted of 175 patients with a total of 186 endoscopically proven gastric cancer lesions. All patients underwent dynamic MDCT (arterial and venous phase) for preoperative staging and underwent surgery or endoscopic treatment. In 129 patients (135 lesions) who were also examined using endoscopic ultrasound, the T staging accuracy was also compared between the two modalities. Two endoscopists independently evaluated the lesion detection rate on virtual gastroscopy images alone and determined the T stage on virtual gastroscopy with MPR images. The T staging included the ability to differentiate T1a from T1b lesions. RESULTS. The overall lesion detection rate was 67.7{\%} (126/186). The detection rates of T1a, T1b, and T2 or deeper were 37.8{\%} (28/74), 75.0{\%} (39/52), and 98.3{\%} (59/60), respectively, showing statistically significant differences (p < 0.001). The T staging accuracies were 82.2{\%} (111/135) using virtual gastroscopy with MPR images and 83.7{\%} (113/135) using endoscopic ultrasound, showing no statistically significant difference (p = 0.850). The main causes of over- and understaging were an ulcer or ulcer scar and poorly differentiated adenocarcinomas, non-solid type, respectively. CONCLUSION. Virtual gastroscopy with MPR imaging is a useful modality in the T staging of gastric cancer.",
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Diagnosis of the invasion depth of gastric cancer using MDCT with virtual gastroscopy : Comparison with staging with endoscopic ultrasound. / Furukawa, Kazuhiro; Miyahara, Ryoji; Itoh, Akihiro; Omiya, Naoki; Hirooka, Yoshiki; Mori, Kensaku; Goto, Hidemi.

In: American Journal of Roentgenology, Vol. 197, No. 4, 01.10.2011, p. 867-875.

Research output: Contribution to journalArticle

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AU - Furukawa, Kazuhiro

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