Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women

Ehab S. Eshak, Hiroyasu Iso, Chigusa Date, Shogo Kikuchi, Yoshiyuki Watanabe, Yasuhiko Wada, Kenji Wakai, Akiko Tamakoshi, Mitsuru Mori, Fumio Sakauchi, Yutaka Motohashi, Ichiro Tsuji, Yosikazu Nakamura, Haruo Mikami, Michiko Kurosawa, Yoshiharu Hoshiyama, Naohito Tanabe, Koji Tamakoshi, Shinkan Tokudome, Koji Suzuki & 10 others Shuji Hashimoto, Takashi Kawamura, Kotarou Ozasa, Tsuneharu Miki, Kiyomi Sakata, Takesumi Yoshimura, Yoshihisa Fujino, Akira Shibata, Naoyuki Okamoto, Hideo Shio

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Dietary fiber protects against coronary heart disease (CHD), but evidence in Asia is limited. We examined the association between dietary fiber intake and mortality from cardiovascular disease (CVD) in a Japanese population in a prospective study of 58,730 Japanesemen andwomenaged 40-79 y in which dietary fiber intake was determined by a self-administered FFQ. The participants were followed up from 1988-1990 to the end of 2003. Hazard ratios (HR) and 95% CI of mortality were calculated per quintile of fiber intake. During the 14-y follow-up, a total of 2080 CVD deaths (983 strokes, 422 CHD, and 675 other CVD) were documented. Total, insoluble, and soluble dietary fiber intakes were inversely associated with risk of mortality from CHD and total CVD for both men and women. For men, the multivariable HR (95% CI) for CHD in the highest vs. the lowest quintiles were 0.81 [(95% CI, 0.61-1.09); P-trend = 0.02], 0.48 [(95% CI, 0.27-0.84); P-trend < 0.001], and 0.71 [(95% CI, 0.41-0.97); P-trend = 0.04] for total, insoluble, and soluble fiber, respectively. The respective HR (95% CI) for women were 0.80 [(95% CI, 0.57-0.97); P-trend = 0.01], 0.49 [(95% CI, 0.27-0.86); P-trend = 0.004], and 0.72 [(95% CI, 0.34-0.99); P-trend = 0.03], respectively. For fiber sources, intakes of fruit and cereal fibers but not vegetable fiber were inversely associated with risk of mortality from CHD. In conclusion, dietary intakes of fiber, both insoluble and soluble fibers, and especially fruit and cereal fibers, may reduce risk of mortality from CHD.

Original languageEnglish
Pages (from-to)1445-1453
Number of pages9
JournalJournal of Nutrition
Volume140
Issue number8
DOIs
Publication statusPublished - 01-08-2010

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Dietary Fiber
Coronary Disease
Cardiovascular Diseases
Mortality
Fruit
Vegetables
Stroke
Prospective Studies
Population

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Eshak, Ehab S. ; Iso, Hiroyasu ; Date, Chigusa ; Kikuchi, Shogo ; Watanabe, Yoshiyuki ; Wada, Yasuhiko ; Wakai, Kenji ; Tamakoshi, Akiko ; Mori, Mitsuru ; Sakauchi, Fumio ; Motohashi, Yutaka ; Tsuji, Ichiro ; Nakamura, Yosikazu ; Mikami, Haruo ; Kurosawa, Michiko ; Hoshiyama, Yoshiharu ; Tanabe, Naohito ; Tamakoshi, Koji ; Tokudome, Shinkan ; Suzuki, Koji ; Hashimoto, Shuji ; Kawamura, Takashi ; Ozasa, Kotarou ; Miki, Tsuneharu ; Sakata, Kiyomi ; Yoshimura, Takesumi ; Fujino, Yoshihisa ; Shibata, Akira ; Okamoto, Naoyuki ; Shio, Hideo. / Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women. In: Journal of Nutrition. 2010 ; Vol. 140, No. 8. pp. 1445-1453.
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abstract = "Dietary fiber protects against coronary heart disease (CHD), but evidence in Asia is limited. We examined the association between dietary fiber intake and mortality from cardiovascular disease (CVD) in a Japanese population in a prospective study of 58,730 Japanesemen andwomenaged 40-79 y in which dietary fiber intake was determined by a self-administered FFQ. The participants were followed up from 1988-1990 to the end of 2003. Hazard ratios (HR) and 95{\%} CI of mortality were calculated per quintile of fiber intake. During the 14-y follow-up, a total of 2080 CVD deaths (983 strokes, 422 CHD, and 675 other CVD) were documented. Total, insoluble, and soluble dietary fiber intakes were inversely associated with risk of mortality from CHD and total CVD for both men and women. For men, the multivariable HR (95{\%} CI) for CHD in the highest vs. the lowest quintiles were 0.81 [(95{\%} CI, 0.61-1.09); P-trend = 0.02], 0.48 [(95{\%} CI, 0.27-0.84); P-trend < 0.001], and 0.71 [(95{\%} CI, 0.41-0.97); P-trend = 0.04] for total, insoluble, and soluble fiber, respectively. The respective HR (95{\%} CI) for women were 0.80 [(95{\%} CI, 0.57-0.97); P-trend = 0.01], 0.49 [(95{\%} CI, 0.27-0.86); P-trend = 0.004], and 0.72 [(95{\%} CI, 0.34-0.99); P-trend = 0.03], respectively. For fiber sources, intakes of fruit and cereal fibers but not vegetable fiber were inversely associated with risk of mortality from CHD. In conclusion, dietary intakes of fiber, both insoluble and soluble fibers, and especially fruit and cereal fibers, may reduce risk of mortality from CHD.",
author = "Eshak, {Ehab S.} and Hiroyasu Iso and Chigusa Date and Shogo Kikuchi and Yoshiyuki Watanabe and Yasuhiko Wada and Kenji Wakai and Akiko Tamakoshi and Mitsuru Mori and Fumio Sakauchi and Yutaka Motohashi and Ichiro Tsuji and Yosikazu Nakamura and Haruo Mikami and Michiko Kurosawa and Yoshiharu Hoshiyama and Naohito Tanabe and Koji Tamakoshi and Shinkan Tokudome and Koji Suzuki and Shuji Hashimoto and Takashi Kawamura and Kotarou Ozasa and Tsuneharu Miki and Kiyomi Sakata and Takesumi Yoshimura and Yoshihisa Fujino and Akira Shibata and Naoyuki Okamoto and Hideo Shio",
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Eshak, ES, Iso, H, Date, C, Kikuchi, S, Watanabe, Y, Wada, Y, Wakai, K, Tamakoshi, A, Mori, M, Sakauchi, F, Motohashi, Y, Tsuji, I, Nakamura, Y, Mikami, H, Kurosawa, M, Hoshiyama, Y, Tanabe, N, Tamakoshi, K, Tokudome, S, Suzuki, K, Hashimoto, S, Kawamura, T, Ozasa, K, Miki, T, Sakata, K, Yoshimura, T, Fujino, Y, Shibata, A, Okamoto, N & Shio, H 2010, 'Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women', Journal of Nutrition, vol. 140, no. 8, pp. 1445-1453. https://doi.org/10.3945/jn.110.122358

Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women. / Eshak, Ehab S.; Iso, Hiroyasu; Date, Chigusa; Kikuchi, Shogo; Watanabe, Yoshiyuki; Wada, Yasuhiko; Wakai, Kenji; Tamakoshi, Akiko; Mori, Mitsuru; Sakauchi, Fumio; Motohashi, Yutaka; Tsuji, Ichiro; Nakamura, Yosikazu; Mikami, Haruo; Kurosawa, Michiko; Hoshiyama, Yoshiharu; Tanabe, Naohito; Tamakoshi, Koji; Tokudome, Shinkan; Suzuki, Koji; Hashimoto, Shuji; Kawamura, Takashi; Ozasa, Kotarou; Miki, Tsuneharu; Sakata, Kiyomi; Yoshimura, Takesumi; Fujino, Yoshihisa; Shibata, Akira; Okamoto, Naoyuki; Shio, Hideo.

In: Journal of Nutrition, Vol. 140, No. 8, 01.08.2010, p. 1445-1453.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women

AU - Eshak, Ehab S.

AU - Iso, Hiroyasu

AU - Date, Chigusa

AU - Kikuchi, Shogo

AU - Watanabe, Yoshiyuki

AU - Wada, Yasuhiko

AU - Wakai, Kenji

AU - Tamakoshi, Akiko

AU - Mori, Mitsuru

AU - Sakauchi, Fumio

AU - Motohashi, Yutaka

AU - Tsuji, Ichiro

AU - Nakamura, Yosikazu

AU - Mikami, Haruo

AU - Kurosawa, Michiko

AU - Hoshiyama, Yoshiharu

AU - Tanabe, Naohito

AU - Tamakoshi, Koji

AU - Tokudome, Shinkan

AU - Suzuki, Koji

AU - Hashimoto, Shuji

AU - Kawamura, Takashi

AU - Ozasa, Kotarou

AU - Miki, Tsuneharu

AU - Sakata, Kiyomi

AU - Yoshimura, Takesumi

AU - Fujino, Yoshihisa

AU - Shibata, Akira

AU - Okamoto, Naoyuki

AU - Shio, Hideo

PY - 2010/8/1

Y1 - 2010/8/1

N2 - Dietary fiber protects against coronary heart disease (CHD), but evidence in Asia is limited. We examined the association between dietary fiber intake and mortality from cardiovascular disease (CVD) in a Japanese population in a prospective study of 58,730 Japanesemen andwomenaged 40-79 y in which dietary fiber intake was determined by a self-administered FFQ. The participants were followed up from 1988-1990 to the end of 2003. Hazard ratios (HR) and 95% CI of mortality were calculated per quintile of fiber intake. During the 14-y follow-up, a total of 2080 CVD deaths (983 strokes, 422 CHD, and 675 other CVD) were documented. Total, insoluble, and soluble dietary fiber intakes were inversely associated with risk of mortality from CHD and total CVD for both men and women. For men, the multivariable HR (95% CI) for CHD in the highest vs. the lowest quintiles were 0.81 [(95% CI, 0.61-1.09); P-trend = 0.02], 0.48 [(95% CI, 0.27-0.84); P-trend < 0.001], and 0.71 [(95% CI, 0.41-0.97); P-trend = 0.04] for total, insoluble, and soluble fiber, respectively. The respective HR (95% CI) for women were 0.80 [(95% CI, 0.57-0.97); P-trend = 0.01], 0.49 [(95% CI, 0.27-0.86); P-trend = 0.004], and 0.72 [(95% CI, 0.34-0.99); P-trend = 0.03], respectively. For fiber sources, intakes of fruit and cereal fibers but not vegetable fiber were inversely associated with risk of mortality from CHD. In conclusion, dietary intakes of fiber, both insoluble and soluble fibers, and especially fruit and cereal fibers, may reduce risk of mortality from CHD.

AB - Dietary fiber protects against coronary heart disease (CHD), but evidence in Asia is limited. We examined the association between dietary fiber intake and mortality from cardiovascular disease (CVD) in a Japanese population in a prospective study of 58,730 Japanesemen andwomenaged 40-79 y in which dietary fiber intake was determined by a self-administered FFQ. The participants were followed up from 1988-1990 to the end of 2003. Hazard ratios (HR) and 95% CI of mortality were calculated per quintile of fiber intake. During the 14-y follow-up, a total of 2080 CVD deaths (983 strokes, 422 CHD, and 675 other CVD) were documented. Total, insoluble, and soluble dietary fiber intakes were inversely associated with risk of mortality from CHD and total CVD for both men and women. For men, the multivariable HR (95% CI) for CHD in the highest vs. the lowest quintiles were 0.81 [(95% CI, 0.61-1.09); P-trend = 0.02], 0.48 [(95% CI, 0.27-0.84); P-trend < 0.001], and 0.71 [(95% CI, 0.41-0.97); P-trend = 0.04] for total, insoluble, and soluble fiber, respectively. The respective HR (95% CI) for women were 0.80 [(95% CI, 0.57-0.97); P-trend = 0.01], 0.49 [(95% CI, 0.27-0.86); P-trend = 0.004], and 0.72 [(95% CI, 0.34-0.99); P-trend = 0.03], respectively. For fiber sources, intakes of fruit and cereal fibers but not vegetable fiber were inversely associated with risk of mortality from CHD. In conclusion, dietary intakes of fiber, both insoluble and soluble fibers, and especially fruit and cereal fibers, may reduce risk of mortality from CHD.

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