Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

Biochemistry, Genetics and Molecular Biology

• Kynurenine 100%
• Quinolinic Acid 100%
• Oxygenase 44%
• Dioxygenase 33%
• Kynureninase 33%
• Neurotoxin 11%
• Astrocyte 11%
• Regulatory Enzymes 11%

Keyphrases

• Acid Formation 100%
• Hydroxylase 44%
• Dioxygenase 33%
• Kynureninase 33%
• 3-hydroxykynurenine 22%
• THP1 11%
• Human Fetal Brain 11%
• U373MG Cells 11%
• Neurotoxin 11%
• Low Activity 11%
• Brain Cells 11%
• Brain Cell Cultures 11%
• Regulatory Enzymes 11%
• U373MG 11%
• Brain Astrocytes 11%

Pharmacology, Toxicology and Pharmaceutical Science

• Kynurenine 3 Monooxygenase 36%
• Kynureninase 27%
• 3 Hydroxyanthranilate 3,4 Dioxygenase 27%
• 3 Hydroxykynurenine 18%
• Neurotoxin 9%