Different sensitivity to chemotherapy between adenocarcinoma and adenosquamous carcinoma in a case of synchronous multicentric gastric cancer

Kazumasa Watanabe; Koichi Achiwa; Hisanori Muto; Naoyuki Arakawa; Kota Aoki; Minoru Kubota; Daisuke Ishikawa; Shin Kunii; Keisuke Goto; Akihiko Okumura

Different sensitivity to chemotherapy between adenocarcinoma and adenosquamous carcinoma in a case of synchronous multicentric gastric cancer

Kazumasa Watanabe, Koichi Achiwa, Hisanori Muto, Naoyuki Arakawa, Kota Aoki, Minoru Kubota, Daisuke Ishikawa, Shin Kunii, Keisuke Goto, Akihiko Okumura

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A 60-year-old man presented with upper gastrointestinal bleeding. We diagnosed double gastric cancer (adenocarcinoma and adenosquamous carcinoma) based on an endoscopic examination. Due to uncontrollable bleeding, total gastrectomy was performed after 4 courses of chemotherapy with S-1 + cisplatin. Histological investigation revealed that no obvious anti-cancer effect was observed in adenosquamous carcinoma (Grade 1), while tumor cells were eliminated in the area of adenocarcinoma (Grade 3). This case clearly demonstrated that sensitivity to chemotherapy was different between adenocarcinoma and adenosquamous carcinoma of the stomach.

Original language	English
Pages (from-to)	408-417
Number of pages	10
Journal	Journal of Japanese Society of Gastroenterology
Volume	109
Issue number	3
Publication status	Published - 03-2012
Externally published	Yes

All Science Journal Classification (ASJC) codes

Gastroenterology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Different sensitivity to chemotherapy between adenocarcinoma and adenosquamous carcinoma in a case of synchronous multicentric gastric cancer",

abstract = "A 60-year-old man presented with upper gastrointestinal bleeding. We diagnosed double gastric cancer (adenocarcinoma and adenosquamous carcinoma) based on an endoscopic examination. Due to uncontrollable bleeding, total gastrectomy was performed after 4 courses of chemotherapy with S-1 + cisplatin. Histological investigation revealed that no obvious anti-cancer effect was observed in adenosquamous carcinoma (Grade 1), while tumor cells were eliminated in the area of adenocarcinoma (Grade 3). This case clearly demonstrated that sensitivity to chemotherapy was different between adenocarcinoma and adenosquamous carcinoma of the stomach.",

author = "Kazumasa Watanabe and Koichi Achiwa and Hisanori Muto and Naoyuki Arakawa and Kota Aoki and Minoru Kubota and Daisuke Ishikawa and Shin Kunii and Keisuke Goto and Akihiko Okumura",

year = "2012",

month = mar,

language = "English",

volume = "109",

pages = "408--417",

journal = "Journal of Japanese Society of Gastroenterology",

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TY - JOUR

T1 - Different sensitivity to chemotherapy between adenocarcinoma and adenosquamous carcinoma in a case of synchronous multicentric gastric cancer

AU - Watanabe, Kazumasa

AU - Achiwa, Koichi

AU - Muto, Hisanori

AU - Arakawa, Naoyuki

AU - Aoki, Kota

AU - Kubota, Minoru

AU - Ishikawa, Daisuke

AU - Kunii, Shin

AU - Goto, Keisuke

AU - Okumura, Akihiko

PY - 2012/3

Y1 - 2012/3

N2 - A 60-year-old man presented with upper gastrointestinal bleeding. We diagnosed double gastric cancer (adenocarcinoma and adenosquamous carcinoma) based on an endoscopic examination. Due to uncontrollable bleeding, total gastrectomy was performed after 4 courses of chemotherapy with S-1 + cisplatin. Histological investigation revealed that no obvious anti-cancer effect was observed in adenosquamous carcinoma (Grade 1), while tumor cells were eliminated in the area of adenocarcinoma (Grade 3). This case clearly demonstrated that sensitivity to chemotherapy was different between adenocarcinoma and adenosquamous carcinoma of the stomach.

AB - A 60-year-old man presented with upper gastrointestinal bleeding. We diagnosed double gastric cancer (adenocarcinoma and adenosquamous carcinoma) based on an endoscopic examination. Due to uncontrollable bleeding, total gastrectomy was performed after 4 courses of chemotherapy with S-1 + cisplatin. Histological investigation revealed that no obvious anti-cancer effect was observed in adenosquamous carcinoma (Grade 1), while tumor cells were eliminated in the area of adenocarcinoma (Grade 3). This case clearly demonstrated that sensitivity to chemotherapy was different between adenocarcinoma and adenosquamous carcinoma of the stomach.

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M3 - Article

C2 - 22398906

AN - SCOPUS:84861514622

SN - 0446-6586

VL - 109

SP - 408

EP - 417

JO - Journal of Japanese Society of Gastroenterology

JF - Journal of Japanese Society of Gastroenterology

IS - 3

ER -

Different sensitivity to chemotherapy between adenocarcinoma and adenosquamous carcinoma in a case of synchronous multicentric gastric cancer

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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