Diffuse periairway thickening in patients with Mikulicz disease

Akihiro Sakashita, Yoshihiro Nishimura, Munenobu Nogami, Emi Kuramoto, Yuko Kono, Masatsugu Yamamoto, Natsumi Tamao, Hiroshi Ohtera, Kazuyuki Kobayashi, Yasuhiro Funada, Teruaki Nishiuma, Yoshikazu Kotani, Yoshiharu Ohno

Research output: Contribution to journalArticlepeer-review


A 70-year-old woman presented with dry mouth, bilateral swelling of the eyelids, and abnormal taste and smell sensations that had persisted for 3 years. She was diagnosed with Mikulicz disease and presented with dyspnea on exertion afterwards. Chest computed tomography and magnetic resonance imaging showed wall thickening of the trachea and bilateral bronchus. Transbronchial needle aspiration showed lymphoproliferative lesion in the tracheobronchus. The patient was treated with corticosteroid, which improved all of her clinical symptoms, computed tomography, and magnetic resonance findings. In this case, we presented a rare condition of coexistent Mikulicz disease with tracheobroncial wall thickening caused by lymphoproliferation without lesions in small airways or lung.

Original languageEnglish
Pages (from-to)213-215
Number of pages3
JournalJournal of Thoracic Imaging
Issue number3
Publication statusPublished - 08-2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Pulmonary and Respiratory Medicine


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