Digital colposcopy for the diagnosis of cervical adenocarcinoma using a narrow band imaging system

Takuma Fujii, Masaru Nakamura, Kaori Kameyama, Miyuki Saito, Hiroshi Nishio, Akiko Ohno, Nobumaru Hirao, Takashi Iwata, Katsumi Tsukazaki, Daisuke Aoki

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Introduction: Although the colposcopic features of cervical glandular disease and cervical adenocarcinoma are not widely well known, unique microvascular patterns are reportedly useful for identifying such diseases. The narrow band imaging (NBI) system used in endoscopy can be used to obtain high-contrast vascular images. Therefore, we examined the utility of NBI colposcopy and compared the results with those of conventional colposcopy. Methods: Twenty-one patients with adenocarinoma in situ or early invasive adenocarci-nomas were examined using digital NBI colposcopy, and the photo records were compared with those of conventional colposcopy. The histological examination and immunohisto-chemistry with anti-CD31 antibody confirmed the microvascular pattern. Results: Digital NBI colposcopy depicted the fine vascular texture on the surface of the cervix more clearly than conventional colposcopy. The vascular pattern was depicted in 86% (18/21) of glandular disease cases. The characteristic fine vascular patterns were critical for identifying cervical glandular diseases. Conclusions: Digital NBI colposcopy was useful for identifying early cervical adeno-carcinoma as well as adenocarcinoma in situ. This system yields cervical glandular disease-related colposcopic findings that may be useful for both clinical and educational purposes.

Original languageEnglish
Pages (from-to)605-610
Number of pages6
JournalInternational Journal of Gynecological Cancer
Volume20
Issue number4
DOIs
Publication statusPublished - 01-05-2010
Externally publishedYes

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Narrow Band Imaging
Colposcopy
Adenocarcinoma
Blood Vessels
Carcinoma in Situ
Cervix Uteri
Endoscopy
Anti-Idiotypic Antibodies

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

Fujii, Takuma ; Nakamura, Masaru ; Kameyama, Kaori ; Saito, Miyuki ; Nishio, Hiroshi ; Ohno, Akiko ; Hirao, Nobumaru ; Iwata, Takashi ; Tsukazaki, Katsumi ; Aoki, Daisuke. / Digital colposcopy for the diagnosis of cervical adenocarcinoma using a narrow band imaging system. In: International Journal of Gynecological Cancer. 2010 ; Vol. 20, No. 4. pp. 605-610.
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abstract = "Introduction: Although the colposcopic features of cervical glandular disease and cervical adenocarcinoma are not widely well known, unique microvascular patterns are reportedly useful for identifying such diseases. The narrow band imaging (NBI) system used in endoscopy can be used to obtain high-contrast vascular images. Therefore, we examined the utility of NBI colposcopy and compared the results with those of conventional colposcopy. Methods: Twenty-one patients with adenocarinoma in situ or early invasive adenocarci-nomas were examined using digital NBI colposcopy, and the photo records were compared with those of conventional colposcopy. The histological examination and immunohisto-chemistry with anti-CD31 antibody confirmed the microvascular pattern. Results: Digital NBI colposcopy depicted the fine vascular texture on the surface of the cervix more clearly than conventional colposcopy. The vascular pattern was depicted in 86{\%} (18/21) of glandular disease cases. The characteristic fine vascular patterns were critical for identifying cervical glandular diseases. Conclusions: Digital NBI colposcopy was useful for identifying early cervical adeno-carcinoma as well as adenocarcinoma in situ. This system yields cervical glandular disease-related colposcopic findings that may be useful for both clinical and educational purposes.",
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Fujii, T, Nakamura, M, Kameyama, K, Saito, M, Nishio, H, Ohno, A, Hirao, N, Iwata, T, Tsukazaki, K & Aoki, D 2010, 'Digital colposcopy for the diagnosis of cervical adenocarcinoma using a narrow band imaging system', International Journal of Gynecological Cancer, vol. 20, no. 4, pp. 605-610. https://doi.org/10.1111/IGC.0b013e3181d98da9

Digital colposcopy for the diagnosis of cervical adenocarcinoma using a narrow band imaging system. / Fujii, Takuma; Nakamura, Masaru; Kameyama, Kaori; Saito, Miyuki; Nishio, Hiroshi; Ohno, Akiko; Hirao, Nobumaru; Iwata, Takashi; Tsukazaki, Katsumi; Aoki, Daisuke.

In: International Journal of Gynecological Cancer, Vol. 20, No. 4, 01.05.2010, p. 605-610.

Research output: Contribution to journalArticle

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T1 - Digital colposcopy for the diagnosis of cervical adenocarcinoma using a narrow band imaging system

AU - Fujii, Takuma

AU - Nakamura, Masaru

AU - Kameyama, Kaori

AU - Saito, Miyuki

AU - Nishio, Hiroshi

AU - Ohno, Akiko

AU - Hirao, Nobumaru

AU - Iwata, Takashi

AU - Tsukazaki, Katsumi

AU - Aoki, Daisuke

PY - 2010/5/1

Y1 - 2010/5/1

N2 - Introduction: Although the colposcopic features of cervical glandular disease and cervical adenocarcinoma are not widely well known, unique microvascular patterns are reportedly useful for identifying such diseases. The narrow band imaging (NBI) system used in endoscopy can be used to obtain high-contrast vascular images. Therefore, we examined the utility of NBI colposcopy and compared the results with those of conventional colposcopy. Methods: Twenty-one patients with adenocarinoma in situ or early invasive adenocarci-nomas were examined using digital NBI colposcopy, and the photo records were compared with those of conventional colposcopy. The histological examination and immunohisto-chemistry with anti-CD31 antibody confirmed the microvascular pattern. Results: Digital NBI colposcopy depicted the fine vascular texture on the surface of the cervix more clearly than conventional colposcopy. The vascular pattern was depicted in 86% (18/21) of glandular disease cases. The characteristic fine vascular patterns were critical for identifying cervical glandular diseases. Conclusions: Digital NBI colposcopy was useful for identifying early cervical adeno-carcinoma as well as adenocarcinoma in situ. This system yields cervical glandular disease-related colposcopic findings that may be useful for both clinical and educational purposes.

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