Abstract
The transfer of IgG antibodies to a causative agent of exanthem subitum (human herpesvirus-6) from mother to infant was examined with an indirect immunofluorescence assay. Of 20 mothers, 85% had the antibody more than 1:10, and the significantly higher level of the antibody was found in the cord blood with a positive rate of 95%. A mean ratio of cord blood to maternal antibody titer was 1.63. A total of 301 sera from healthy individuals was examined for the age-specific prevalence of antibody to the virus. In the first 2 months of life, 87% of infants had the antibody; the positive rate and the level of antibody decreased during the first 6 months of life with the lowest positive rate of 6% at 4 to 5 months of age. After 6 months of age, they increased gradually and reached the highest level at 1 year of age with the positive rate of 86%. From 2 years of age, the prevalence of the antibody was almost stable (69% to 76%) and similar to those in adolescents and adults.
| Original language | English |
|---|---|
| Pages (from-to) | 675-677 |
| Number of pages | 3 |
| Journal | Pediatrics |
| Volume | 84 |
| Issue number | 4 |
| Publication status | Published - 01-01-1989 |
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All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
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Distribution of antibodies to a causative agent of exanthem subitum (human herpesvirus-6) in healthy individuals. / Yoshikawa, T.; Suga, S.; Asano, Y.; Yazaki, T.; Kodama, H.; Ozaki, T.
In: Pediatrics, Vol. 84, No. 4, 01.01.1989, p. 675-677.Research output: Contribution to journal › Article
TY - JOUR
T1 - Distribution of antibodies to a causative agent of exanthem subitum (human herpesvirus-6) in healthy individuals
AU - Yoshikawa, T.
AU - Suga, S.
AU - Asano, Y.
AU - Yazaki, T.
AU - Kodama, H.
AU - Ozaki, T.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - The transfer of IgG antibodies to a causative agent of exanthem subitum (human herpesvirus-6) from mother to infant was examined with an indirect immunofluorescence assay. Of 20 mothers, 85% had the antibody more than 1:10, and the significantly higher level of the antibody was found in the cord blood with a positive rate of 95%. A mean ratio of cord blood to maternal antibody titer was 1.63. A total of 301 sera from healthy individuals was examined for the age-specific prevalence of antibody to the virus. In the first 2 months of life, 87% of infants had the antibody; the positive rate and the level of antibody decreased during the first 6 months of life with the lowest positive rate of 6% at 4 to 5 months of age. After 6 months of age, they increased gradually and reached the highest level at 1 year of age with the positive rate of 86%. From 2 years of age, the prevalence of the antibody was almost stable (69% to 76%) and similar to those in adolescents and adults.
AB - The transfer of IgG antibodies to a causative agent of exanthem subitum (human herpesvirus-6) from mother to infant was examined with an indirect immunofluorescence assay. Of 20 mothers, 85% had the antibody more than 1:10, and the significantly higher level of the antibody was found in the cord blood with a positive rate of 95%. A mean ratio of cord blood to maternal antibody titer was 1.63. A total of 301 sera from healthy individuals was examined for the age-specific prevalence of antibody to the virus. In the first 2 months of life, 87% of infants had the antibody; the positive rate and the level of antibody decreased during the first 6 months of life with the lowest positive rate of 6% at 4 to 5 months of age. After 6 months of age, they increased gradually and reached the highest level at 1 year of age with the positive rate of 86%. From 2 years of age, the prevalence of the antibody was almost stable (69% to 76%) and similar to those in adolescents and adults.
UR - http://www.scopus.com/inward/record.url?scp=0024455232&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024455232&partnerID=8YFLogxK
M3 - Article
C2 - 2550877
AN - SCOPUS:0024455232
VL - 84
SP - 675
EP - 677
JO - Pediatrics
JF - Pediatrics
SN - 0031-4005
IS - 4
ER -