Does quazepam influence sleep and daytime activity in healthy adults?

A pilot study using actigraph was conducted to assess the effects of a 1-week repeated administration of 15 mg of quazepam on the sleep and daytime activity of six healthy adults. The nocturnal sleep time gradually increased during quazepam administration, and a significant difference from the baseline was noted on the seventh day of administration. There was no significant difference in the daytime activity before and after the administration. Quazepam and its active metabolites appear to have acted on the level not affecting the daytime activity but prolonging the nocturnal sleep time through their interactions.