Does quazepam influence sleep and daytime activity in healthy adults?

Kazunori Kusunoki, Tsuyoshi Kitajima, Norio Ozaki

Research output: Contribution to journalArticlepeer-review


A pilot study using actigraph was conducted to assess the effects of a 1-week repeated administration of 15 mg of quazepam on the sleep and daytime activity of six healthy adults. The nocturnal sleep time gradually increased during quazepam administration, and a significant difference from the baseline was noted on the seventh day of administration. There was no significant difference in the daytime activity before and after the administration. Quazepam and its active metabolites appear to have acted on the level not affecting the daytime activity but prolonging the nocturnal sleep time through their interactions.

Original languageEnglish
Pages (from-to)171-172
Number of pages2
JournalSleep and Biological Rhythms
Issue number2
Publication statusPublished - 01-03-2003

All Science Journal Classification (ASJC) codes

  • Physiology
  • Neuropsychology and Physiological Psychology
  • Neurology
  • Physiology (medical)


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