Early and late optical coherence tomography findings following everolimus-eluting bioresorbable vascular scaffold implantation in myocardial infarction: A preliminary report

Antonios Karanasos, Takashi Muramatsu, Roberto Diletti, Sjoerd Nauta, Yoshinobu Onuma, Mattie Lenzen, Shimpei Nakatani, Nicolas M. Van Mieghem, Carl Schultz, Peter P. de Jaegere, Patrick W. Serruys, Felix Zijlstra, Evelyn Regar, Robert Jan van Geuns

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Introduction: Although bioresorbable vascular scaffolds (BVS) have been used with promising results in patients with stable and unstable angina, little is known about the acute vascular response following BVS implantation in myocardial infarction. We present angiographic and OCT findings from the first patients undergoing bioresorbable vascular scaffold (BVS) implantation for non-ST-elevation myocardial infarction (NSTEMI) or ST-elevation myocardial infarction (STEMI) in our institution. Methods: The first 5 patients with NSTEMI and the first 5 patients with STEMI who underwent BVS implantation in our institution, followed by optical coherence tomography (OCT) imaging of the treated culprit vessel, were included in this series. All patients underwent angiographic analysis pre- and post- BVS implantation, as well as OCT analysis, including qualitative and quantitative assessment. Results: Implantation was successful in all cases, as assessed by angiography and OCT. There were no cases with coronary spasm, distal embolization or no-reflow. No adverse clinical events were recorded in any patient at the 6-month follow up. Specific illustrative cases demonstrating the challenges of BVS implantation in myocardial infarction are presented. Conclusions: BVS implantation can potentially be used in the setting of thrombotic lesions encountered in myocardial infarction; however, the role of this treatment approach warrants systematic evaluation in prospective studies.

Original languageEnglish
Pages (from-to)125-135
Number of pages11
JournalHellenic Journal of Cardiology
Volume56
Issue number2
Publication statusPublished - 01-03-2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Early and late optical coherence tomography findings following everolimus-eluting bioresorbable vascular scaffold implantation in myocardial infarction: A preliminary report'. Together they form a unique fingerprint.

  • Cite this

    Karanasos, A., Muramatsu, T., Diletti, R., Nauta, S., Onuma, Y., Lenzen, M., Nakatani, S., Van Mieghem, N. M., Schultz, C., de Jaegere, P. P., Serruys, P. W., Zijlstra, F., Regar, E., & van Geuns, R. J. (2015). Early and late optical coherence tomography findings following everolimus-eluting bioresorbable vascular scaffold implantation in myocardial infarction: A preliminary report. Hellenic Journal of Cardiology, 56(2), 125-135.