Eating fast leads to insulin resistance: Findings in middle-aged Japanese men and women

Rei Otsuka, Koji Tamakoshi, Hiroshi Yatsuya, Keiko Wada, Kunihiro Matsushita, Pei OuYang, Yo Hotta, Seiko Takefuji, Hirotsugu Mitsuhashi, Kaichiro Sugiura, Satoshi Sasaki, John G. Kral, Hideaki Toyoshima

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.

Original languageEnglish
Pages (from-to)154-159
Number of pages6
JournalPreventive Medicine
Volume46
Issue number2
DOIs
Publication statusPublished - 01-02-2008
Externally publishedYes

Fingerprint

Insulin Resistance
Eating
Energy Intake
Homeostasis
Life Style
Blood Glucose
Cross-Sectional Studies
Regression Analysis
Insulin
Diet

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Otsuka, R., Tamakoshi, K., Yatsuya, H., Wada, K., Matsushita, K., OuYang, P., ... Toyoshima, H. (2008). Eating fast leads to insulin resistance: Findings in middle-aged Japanese men and women. Preventive Medicine, 46(2), 154-159. https://doi.org/10.1016/j.ypmed.2007.07.031
Otsuka, Rei ; Tamakoshi, Koji ; Yatsuya, Hiroshi ; Wada, Keiko ; Matsushita, Kunihiro ; OuYang, Pei ; Hotta, Yo ; Takefuji, Seiko ; Mitsuhashi, Hirotsugu ; Sugiura, Kaichiro ; Sasaki, Satoshi ; Kral, John G. ; Toyoshima, Hideaki. / Eating fast leads to insulin resistance : Findings in middle-aged Japanese men and women. In: Preventive Medicine. 2008 ; Vol. 46, No. 2. pp. 154-159.
@article{f569e3d4aa094aadb07377f608ba30f8,
title = "Eating fast leads to insulin resistance: Findings in middle-aged Japanese men and women",
abstract = "Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75{\%} clerical, and 25{\%} manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.",
author = "Rei Otsuka and Koji Tamakoshi and Hiroshi Yatsuya and Keiko Wada and Kunihiro Matsushita and Pei OuYang and Yo Hotta and Seiko Takefuji and Hirotsugu Mitsuhashi and Kaichiro Sugiura and Satoshi Sasaki and Kral, {John G.} and Hideaki Toyoshima",
year = "2008",
month = "2",
day = "1",
doi = "10.1016/j.ypmed.2007.07.031",
language = "English",
volume = "46",
pages = "154--159",
journal = "Preventive Medicine",
issn = "0091-7435",
publisher = "Academic Press Inc.",
number = "2",

}

Otsuka, R, Tamakoshi, K, Yatsuya, H, Wada, K, Matsushita, K, OuYang, P, Hotta, Y, Takefuji, S, Mitsuhashi, H, Sugiura, K, Sasaki, S, Kral, JG & Toyoshima, H 2008, 'Eating fast leads to insulin resistance: Findings in middle-aged Japanese men and women', Preventive Medicine, vol. 46, no. 2, pp. 154-159. https://doi.org/10.1016/j.ypmed.2007.07.031

Eating fast leads to insulin resistance : Findings in middle-aged Japanese men and women. / Otsuka, Rei; Tamakoshi, Koji; Yatsuya, Hiroshi; Wada, Keiko; Matsushita, Kunihiro; OuYang, Pei; Hotta, Yo; Takefuji, Seiko; Mitsuhashi, Hirotsugu; Sugiura, Kaichiro; Sasaki, Satoshi; Kral, John G.; Toyoshima, Hideaki.

In: Preventive Medicine, Vol. 46, No. 2, 01.02.2008, p. 154-159.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Eating fast leads to insulin resistance

T2 - Findings in middle-aged Japanese men and women

AU - Otsuka, Rei

AU - Tamakoshi, Koji

AU - Yatsuya, Hiroshi

AU - Wada, Keiko

AU - Matsushita, Kunihiro

AU - OuYang, Pei

AU - Hotta, Yo

AU - Takefuji, Seiko

AU - Mitsuhashi, Hirotsugu

AU - Sugiura, Kaichiro

AU - Sasaki, Satoshi

AU - Kral, John G.

AU - Toyoshima, Hideaki

PY - 2008/2/1

Y1 - 2008/2/1

N2 - Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.

AB - Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.

UR - http://www.scopus.com/inward/record.url?scp=38849142012&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38849142012&partnerID=8YFLogxK

U2 - 10.1016/j.ypmed.2007.07.031

DO - 10.1016/j.ypmed.2007.07.031

M3 - Article

C2 - 17822753

AN - SCOPUS:38849142012

VL - 46

SP - 154

EP - 159

JO - Preventive Medicine

JF - Preventive Medicine

SN - 0091-7435

IS - 2

ER -