TY - JOUR
T1 - Eating fast leads to insulin resistance
T2 - Findings in middle-aged Japanese men and women
AU - Otsuka, Rei
AU - Tamakoshi, Koji
AU - Yatsuya, Hiroshi
AU - Wada, Keiko
AU - Matsushita, Kunihiro
AU - OuYang, Pei
AU - Hotta, Yo
AU - Takefuji, Seiko
AU - Mitsuhashi, Hirotsugu
AU - Sugiura, Kaichiro
AU - Sasaki, Satoshi
AU - Kral, John G.
AU - Toyoshima, Hideaki
N1 - Funding Information:
This work is supported in part by grants to Hideaki Toyoshima (17390185), Koji Tamakoshi (18590594), and Hiroshi Yatsuya (17790384) from the Ministry of Education, Culture, Sports, Science and Technology and the Japan Atherosclerosis Prevention Fund (JAPF).
PY - 2008/2
Y1 - 2008/2
N2 - Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.
AB - Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.
UR - https://www.scopus.com/pages/publications/38849142012
UR - https://www.scopus.com/pages/publications/38849142012#tab=citedBy
U2 - 10.1016/j.ypmed.2007.07.031
DO - 10.1016/j.ypmed.2007.07.031
M3 - Article
C2 - 17822753
AN - SCOPUS:38849142012
SN - 0091-7435
VL - 46
SP - 154
EP - 159
JO - Preventive Medicine
JF - Preventive Medicine
IS - 2
ER -
