TY - JOUR
T1 - Effect of axial length on laser spot size during photodynamic therapy
T2 - An experimental study in monkeys
AU - Kondo, Mineo
AU - Ito, Yasuki
AU - Miyata, Kentaro
AU - Kondo, Nagako
AU - Ishikawa, Kohei
AU - Terasaki, Hiroko
N1 - Funding Information:
Supported by a Grant-in Aid 16591747 (M.K.) and 16390497 (H.T.) from the Ministry of Education, Science, Sports and Culture, Japan.
PY - 2006/1
Y1 - 2006/1
N2 - PURPOSE: To investigate the effect of shorter axial length on the laser spot size and laser energy during photodynamic therapy (PDT) in monkeys. DESIGN: Experimental study with four rhesus monkeys. METHODS: PDT was performed on the normal retina of monkeys whose ocular axial lengths are shorter (19.55 to 20.25 mm) than that of humans. After the PDT, the eyes were enucleated, and the diameter of the irradiated laser spot was measured with a microcaliper. RESULTS: The area of actual laser spot was only 0.56 to 0.61 times of the planned area, which indicated that the laser energy/area was 1.64 to 1.78 times more intense than planned initially. CONCLUSION: These results are the in vivo demonstration that the diameter of PDT laser spot is smaller for eyes with shorter axial lengths.
AB - PURPOSE: To investigate the effect of shorter axial length on the laser spot size and laser energy during photodynamic therapy (PDT) in monkeys. DESIGN: Experimental study with four rhesus monkeys. METHODS: PDT was performed on the normal retina of monkeys whose ocular axial lengths are shorter (19.55 to 20.25 mm) than that of humans. After the PDT, the eyes were enucleated, and the diameter of the irradiated laser spot was measured with a microcaliper. RESULTS: The area of actual laser spot was only 0.56 to 0.61 times of the planned area, which indicated that the laser energy/area was 1.64 to 1.78 times more intense than planned initially. CONCLUSION: These results are the in vivo demonstration that the diameter of PDT laser spot is smaller for eyes with shorter axial lengths.
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U2 - 10.1016/j.ajo.2005.08.016
DO - 10.1016/j.ajo.2005.08.016
M3 - Article
C2 - 16387010
AN - SCOPUS:29544451658
SN - 0002-9394
VL - 141
SP - 214
EP - 215
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 1
ER -