Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donors

Y. Morishima, T. Kawase, M. Malkki, E. W. Petersdorf

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Population-based differences in clinical outcome after unrelated donor hematopoietic cell transplantation suggest that the significance of human leukocyte antigen (HLA) mismatching may be related to locus-specific and allele-specific differences that distinguish ethnically diverse transplant donors and recipients. We studied the risks associated with HLA-A locus mismatching in two large transplant populations from the International Histocompatibility Working Group in hematopoietic cell transplantation data set to better understand permissible and nonpermissible HLA-A mismatches.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalTissue Antigens
Volume69
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 04-2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Biochemistry
  • Genetics

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