Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donors

Y. Morishima; T. Kawase; M. Malkki; E. W. Petersdorf

doi:10.1111/j.1399-0039.2006.759_3.x

Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donors

Y. Morishima
, T. Kawase
, M. Malkki
, E. W. Petersdorf

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Population-based differences in clinical outcome after unrelated donor hematopoietic cell transplantation suggest that the significance of human leukocyte antigen (HLA) mismatching may be related to locus-specific and allele-specific differences that distinguish ethnically diverse transplant donors and recipients. We studied the risks associated with HLA-A locus mismatching in two large transplant populations from the International Histocompatibility Working Group in hematopoietic cell transplantation data set to better understand permissible and nonpermissible HLA-A mismatches.

Original language	English
Pages (from-to)	31-35
Number of pages	5
Journal	Tissue Antigens
Volume	69
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1111/j.1399-0039.2006.759_3.x
Publication status	Published - 04-2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Biochemistry
Immunology
Genetics

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10.1111/j.1399-0039.2006.759_3.x

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AB - Population-based differences in clinical outcome after unrelated donor hematopoietic cell transplantation suggest that the significance of human leukocyte antigen (HLA) mismatching may be related to locus-specific and allele-specific differences that distinguish ethnically diverse transplant donors and recipients. We studied the risks associated with HLA-A locus mismatching in two large transplant populations from the International Histocompatibility Working Group in hematopoietic cell transplantation data set to better understand permissible and nonpermissible HLA-A mismatches.

KW - HLA-A2

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Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donors

Abstract

All Science Journal Classification (ASJC) codes

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