Effect of parenteral hydration therapy based on the Japanese national clinical guideline on quality of life, discomfort, and symptom intensity in patients with advanced cancer

Takashi Yamaguchi, Tatsuya Morita, Takuya Shinjo, Satoshi Inoue, Chizuko Takigawa, Etsuko Aruga, Kazuhiko Tani, Takashi Hara, Yoichiro Tamura, Akihiko Suga, Seiji Adachi, Hideki Katayama, Iwao Osaka, Yoshiyuki Saito, Nobuhisa Nakajima, Takashi Higashiguchi, Tatsuhiko Hayashi, Takeshi Okabe, Hiroyuki Kohara, Tomohiro TamakiYoshikazu Chinone, Hideki Aragane, Yoshiaki Kanai, Natsuki Tokura, Takuhiro Yamaguchi, Takashi Asada, Yosuke Uchitomi

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Context: Although an evidence-based clinical guideline for parenteral hydration therapy was established in Japan, the efficacy of the guideline has not been assessed. Objectives: Our purpose was to explore the effect of parenteral hydration therapy based on this clinical guideline on quality of life (QoL), discomfort, symptoms, and fluid retention signs in patients with advanced cancer. Methods: This multicenter, prospective, observational study included 161 patients with advanced abdominal cancer who received guideline-based hydration therapy. We evaluated the longitudinal changes of the global QoL (Item 30 of European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire-C30); the Discomfort Scale; the intensity of seven physical symptoms; and the severity of fluid retention signs. We also evaluated patient satisfaction and the feeling of benefit from hydration one week after the study commenced, and bronchial secretions, hyperactive delirium, communication capacity, and agitation 48 hours before a patient's death. Results: The global QoL, the Discomfort Scale, and the intensities of all physical symptoms, except for vomiting and drowsiness, were stable throughout the study period. More than 80% of patients maintained all fluid retention signs. Patient global satisfaction was 76.4 (0-100) and feeling of benefit was 5.43 (range 0-7). Conclusion: Guideline-based parenteral hydration therapy contributed to maintaining global QoL and provided satisfaction and a feeling of benefit without increasing discomfort and worsening symptoms and fluid retention signs in patients with advanced cancer.

Original languageEnglish
Pages (from-to)1001-1012
Number of pages12
JournalJournal of Pain and Symptom Management
Volume43
Issue number6
DOIs
Publication statusPublished - 01-06-2012

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Quality of Life
Guidelines
Emotions
Neoplasms
Patient Satisfaction
Therapeutics
Delirium
Sleep Stages
Vomiting
Observational Studies
Japan
Communication
Organizations
Prospective Studies
Research

All Science Journal Classification (ASJC) codes

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Yamaguchi, Takashi ; Morita, Tatsuya ; Shinjo, Takuya ; Inoue, Satoshi ; Takigawa, Chizuko ; Aruga, Etsuko ; Tani, Kazuhiko ; Hara, Takashi ; Tamura, Yoichiro ; Suga, Akihiko ; Adachi, Seiji ; Katayama, Hideki ; Osaka, Iwao ; Saito, Yoshiyuki ; Nakajima, Nobuhisa ; Higashiguchi, Takashi ; Hayashi, Tatsuhiko ; Okabe, Takeshi ; Kohara, Hiroyuki ; Tamaki, Tomohiro ; Chinone, Yoshikazu ; Aragane, Hideki ; Kanai, Yoshiaki ; Tokura, Natsuki ; Yamaguchi, Takuhiro ; Asada, Takashi ; Uchitomi, Yosuke. / Effect of parenteral hydration therapy based on the Japanese national clinical guideline on quality of life, discomfort, and symptom intensity in patients with advanced cancer. In: Journal of Pain and Symptom Management. 2012 ; Vol. 43, No. 6. pp. 1001-1012.
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abstract = "Context: Although an evidence-based clinical guideline for parenteral hydration therapy was established in Japan, the efficacy of the guideline has not been assessed. Objectives: Our purpose was to explore the effect of parenteral hydration therapy based on this clinical guideline on quality of life (QoL), discomfort, symptoms, and fluid retention signs in patients with advanced cancer. Methods: This multicenter, prospective, observational study included 161 patients with advanced abdominal cancer who received guideline-based hydration therapy. We evaluated the longitudinal changes of the global QoL (Item 30 of European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire-C30); the Discomfort Scale; the intensity of seven physical symptoms; and the severity of fluid retention signs. We also evaluated patient satisfaction and the feeling of benefit from hydration one week after the study commenced, and bronchial secretions, hyperactive delirium, communication capacity, and agitation 48 hours before a patient's death. Results: The global QoL, the Discomfort Scale, and the intensities of all physical symptoms, except for vomiting and drowsiness, were stable throughout the study period. More than 80{\%} of patients maintained all fluid retention signs. Patient global satisfaction was 76.4 (0-100) and feeling of benefit was 5.43 (range 0-7). Conclusion: Guideline-based parenteral hydration therapy contributed to maintaining global QoL and provided satisfaction and a feeling of benefit without increasing discomfort and worsening symptoms and fluid retention signs in patients with advanced cancer.",
author = "Takashi Yamaguchi and Tatsuya Morita and Takuya Shinjo and Satoshi Inoue and Chizuko Takigawa and Etsuko Aruga and Kazuhiko Tani and Takashi Hara and Yoichiro Tamura and Akihiko Suga and Seiji Adachi and Hideki Katayama and Iwao Osaka and Yoshiyuki Saito and Nobuhisa Nakajima and Takashi Higashiguchi and Tatsuhiko Hayashi and Takeshi Okabe and Hiroyuki Kohara and Tomohiro Tamaki and Yoshikazu Chinone and Hideki Aragane and Yoshiaki Kanai and Natsuki Tokura and Takuhiro Yamaguchi and Takashi Asada and Yosuke Uchitomi",
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Yamaguchi, T, Morita, T, Shinjo, T, Inoue, S, Takigawa, C, Aruga, E, Tani, K, Hara, T, Tamura, Y, Suga, A, Adachi, S, Katayama, H, Osaka, I, Saito, Y, Nakajima, N, Higashiguchi, T, Hayashi, T, Okabe, T, Kohara, H, Tamaki, T, Chinone, Y, Aragane, H, Kanai, Y, Tokura, N, Yamaguchi, T, Asada, T & Uchitomi, Y 2012, 'Effect of parenteral hydration therapy based on the Japanese national clinical guideline on quality of life, discomfort, and symptom intensity in patients with advanced cancer', Journal of Pain and Symptom Management, vol. 43, no. 6, pp. 1001-1012. https://doi.org/10.1016/j.jpainsymman.2011.06.028

Effect of parenteral hydration therapy based on the Japanese national clinical guideline on quality of life, discomfort, and symptom intensity in patients with advanced cancer. / Yamaguchi, Takashi; Morita, Tatsuya; Shinjo, Takuya; Inoue, Satoshi; Takigawa, Chizuko; Aruga, Etsuko; Tani, Kazuhiko; Hara, Takashi; Tamura, Yoichiro; Suga, Akihiko; Adachi, Seiji; Katayama, Hideki; Osaka, Iwao; Saito, Yoshiyuki; Nakajima, Nobuhisa; Higashiguchi, Takashi; Hayashi, Tatsuhiko; Okabe, Takeshi; Kohara, Hiroyuki; Tamaki, Tomohiro; Chinone, Yoshikazu; Aragane, Hideki; Kanai, Yoshiaki; Tokura, Natsuki; Yamaguchi, Takuhiro; Asada, Takashi; Uchitomi, Yosuke.

In: Journal of Pain and Symptom Management, Vol. 43, No. 6, 01.06.2012, p. 1001-1012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of parenteral hydration therapy based on the Japanese national clinical guideline on quality of life, discomfort, and symptom intensity in patients with advanced cancer

AU - Yamaguchi, Takashi

AU - Morita, Tatsuya

AU - Shinjo, Takuya

AU - Inoue, Satoshi

AU - Takigawa, Chizuko

AU - Aruga, Etsuko

AU - Tani, Kazuhiko

AU - Hara, Takashi

AU - Tamura, Yoichiro

AU - Suga, Akihiko

AU - Adachi, Seiji

AU - Katayama, Hideki

AU - Osaka, Iwao

AU - Saito, Yoshiyuki

AU - Nakajima, Nobuhisa

AU - Higashiguchi, Takashi

AU - Hayashi, Tatsuhiko

AU - Okabe, Takeshi

AU - Kohara, Hiroyuki

AU - Tamaki, Tomohiro

AU - Chinone, Yoshikazu

AU - Aragane, Hideki

AU - Kanai, Yoshiaki

AU - Tokura, Natsuki

AU - Yamaguchi, Takuhiro

AU - Asada, Takashi

AU - Uchitomi, Yosuke

PY - 2012/6/1

Y1 - 2012/6/1

N2 - Context: Although an evidence-based clinical guideline for parenteral hydration therapy was established in Japan, the efficacy of the guideline has not been assessed. Objectives: Our purpose was to explore the effect of parenteral hydration therapy based on this clinical guideline on quality of life (QoL), discomfort, symptoms, and fluid retention signs in patients with advanced cancer. Methods: This multicenter, prospective, observational study included 161 patients with advanced abdominal cancer who received guideline-based hydration therapy. We evaluated the longitudinal changes of the global QoL (Item 30 of European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire-C30); the Discomfort Scale; the intensity of seven physical symptoms; and the severity of fluid retention signs. We also evaluated patient satisfaction and the feeling of benefit from hydration one week after the study commenced, and bronchial secretions, hyperactive delirium, communication capacity, and agitation 48 hours before a patient's death. Results: The global QoL, the Discomfort Scale, and the intensities of all physical symptoms, except for vomiting and drowsiness, were stable throughout the study period. More than 80% of patients maintained all fluid retention signs. Patient global satisfaction was 76.4 (0-100) and feeling of benefit was 5.43 (range 0-7). Conclusion: Guideline-based parenteral hydration therapy contributed to maintaining global QoL and provided satisfaction and a feeling of benefit without increasing discomfort and worsening symptoms and fluid retention signs in patients with advanced cancer.

AB - Context: Although an evidence-based clinical guideline for parenteral hydration therapy was established in Japan, the efficacy of the guideline has not been assessed. Objectives: Our purpose was to explore the effect of parenteral hydration therapy based on this clinical guideline on quality of life (QoL), discomfort, symptoms, and fluid retention signs in patients with advanced cancer. Methods: This multicenter, prospective, observational study included 161 patients with advanced abdominal cancer who received guideline-based hydration therapy. We evaluated the longitudinal changes of the global QoL (Item 30 of European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire-C30); the Discomfort Scale; the intensity of seven physical symptoms; and the severity of fluid retention signs. We also evaluated patient satisfaction and the feeling of benefit from hydration one week after the study commenced, and bronchial secretions, hyperactive delirium, communication capacity, and agitation 48 hours before a patient's death. Results: The global QoL, the Discomfort Scale, and the intensities of all physical symptoms, except for vomiting and drowsiness, were stable throughout the study period. More than 80% of patients maintained all fluid retention signs. Patient global satisfaction was 76.4 (0-100) and feeling of benefit was 5.43 (range 0-7). Conclusion: Guideline-based parenteral hydration therapy contributed to maintaining global QoL and provided satisfaction and a feeling of benefit without increasing discomfort and worsening symptoms and fluid retention signs in patients with advanced cancer.

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U2 - 10.1016/j.jpainsymman.2011.06.028

DO - 10.1016/j.jpainsymman.2011.06.028

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VL - 43

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JO - Journal of Pain and Symptom Management

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