Effect of reconstruction algorithm on image quality and identification of ground-glass opacities and partly solid nodules on low-dose thin-section CT: Experimental study using chest phantom

Hisanobu Koyama, Yoshiharu Ohno, Atsushi A. Kono, Akiko Kusaka, Minoru Konishi, Masaru Yoshii, Kazuro Sugimura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose: The purpose of this study was to assess the influence of reconstruction algorithm on identification and image quality of ground-glass opacities (GGOs) and partly solid nodules on low-dose thin-section CT. Materials and methods: A chest CT phantom including simulated GGOs and partly solid nodules was scanned with five different tube currents and reconstructed by using standard (A) and newly developed (B) high-resolution reconstruction algorithms, followed by visually assessment of identification and image quality of GGOs and partly solid nodules by two chest radiologists. Inter-observer agreement, ROC analysis and ANOVA were performed to compare identification and image quality of each data set with those of the standard reference. The standard reference used 120 mA s in conjunction with reconstruction algorithm A. Results: Kappa values (κ) of overall identification and image qualities were substantial or almost perfect (0.60 < κ). Assessment of identification showed that area under the curve of 25 mA reconstructed with reconstruction algorithm A was significantly lower than that of standard reference (p < 0.05), while assessment of image quality indicated that 50 mA s reconstructed with reconstruction algorithm A and 25 mA s reconstructed with both reconstruction algorithms were significantly lower than standard reference (p < 0.05). Conclusion: Reconstruction algorithm may be an important factor for identification and image quality of ground-glass opacities and partly solid nodules on low-dose CT examination.

Original languageEnglish
Pages (from-to)500-507
Number of pages8
JournalEuropean journal of radiology
Volume74
Issue number3
DOIs
Publication statusPublished - 06-2010

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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