TY - JOUR
T1 - Effects of administration of Clostridium butyricum to patients receiving long-term feeding
AU - Ito, I.
AU - Hayashi, T.
AU - Iguchi, A.
AU - Endo, H.
AU - Nakao, M.
AU - Kato, S.
AU - Nabeshima, T.
AU - Ogura, Y.
PY - 1997
Y1 - 1997
N2 - In patients who require total parenteral or enteral nutrition the intestinal lining may atrophy and the ability to absorb nutrients may be lost. To prevent atrophy of the small intestine, we administered a suspension of Clostridium butyricum to elderly patients receiving tube feeding, and then measured the activation of serum diamine oxidase and the number, form, water content, and bacteria content of stools, indicators of intestinal structure. We found a significant increase in diamine oxidase activity and an improvement in stool condition: the number of stools per day decreased, form improved, and water content and the number of aerobic bacteria decreased significantly. These results indicate that in patients receiving long-term tube feeding administration of Clostridium can restore condition to a near- normal state.
AB - In patients who require total parenteral or enteral nutrition the intestinal lining may atrophy and the ability to absorb nutrients may be lost. To prevent atrophy of the small intestine, we administered a suspension of Clostridium butyricum to elderly patients receiving tube feeding, and then measured the activation of serum diamine oxidase and the number, form, water content, and bacteria content of stools, indicators of intestinal structure. We found a significant increase in diamine oxidase activity and an improvement in stool condition: the number of stools per day decreased, form improved, and water content and the number of aerobic bacteria decreased significantly. These results indicate that in patients receiving long-term tube feeding administration of Clostridium can restore condition to a near- normal state.
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U2 - 10.3143/geriatrics.34.298
DO - 10.3143/geriatrics.34.298
M3 - Article
C2 - 9212685
AN - SCOPUS:0031007195
SN - 0300-9173
VL - 34
SP - 298
EP - 304
JO - Japanese Journal of Geriatrics
JF - Japanese Journal of Geriatrics
IS - 4
ER -