TY - JOUR
T1 - Effects of case volume on short- and long-term outcomes following cadaveric lung transplantation in Japan
AU - Chida, Masayuki
AU - Inoue, Takashi
AU - Nakajima, Takahiro
AU - Okada, Yoshinori
AU - Oishi, Hisashi
AU - Nakajima, Jun
AU - Sato, Masaaki
AU - Yoshino, Ichiro
AU - Suzuki, Hidemi
AU - Nakajima, Daisuke
AU - Shintani, Yasushi
AU - Kanou, Takashi
AU - Toyooka, Shinichi
AU - Miyoshi, Kentaroh
AU - Shiraishi, Takeshi
AU - Sato, Toshihiko
AU - Matsumoto, Keitaro
AU - Nagayasu, Takeshi
AU - Hoshikawa, Yasushi
AU - Matsuda, Yasushi
AU - Maeda, Sumiko
AU - Date, Hiroshi
N1 - Publisher Copyright:
© Journal of Thoracic Disease. All rights reserved.
PY - 2024/2
Y1 - 2024/2
N2 - Background: Despite the low number of lung transplantations (LTs) in Japan, 10 LT facilities are accredited and good outcomes have been reported. A database review was conducted to clarify the impact of case volume at LT facilities in Japan on short- and long-term outcomes. Methods: All cadaveric LT cases treated between 2000 and 2021 in Japan were analyzed using the database of the Japanese Society of Lung and Heart-Lung Transplantation (JSLHT). The nine institutions represented were categorized into the low-volume (LV; <80 cumulative LT cases, <8 LTs/year, n=5) and high-volume (HV; ≥80 cumulative LT cases, ≥8 LTs/year, n=4) centers. Ninety-day and 1-year mortality, as well as 5- and 10-year survival data were evaluated. Results: A total of 658 cadaveric LTs were performed at the nine institutions. The 90-day rates of mortality at the HV and LV centers were 3.5% and 3.9%, respectively (P=0.801), while the 1-year mortality rates were 9.2% and 11.5%, respectively (P=0.199). Additionally, log-rank analysis of Kaplan-Meier curves showing case volume did not reveal a significant difference in long-term survival between the HV and LV centers (P=0.272), though the LV centers had wide differences for long-term outcomes (P=0.030). Conclusions: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers.
AB - Background: Despite the low number of lung transplantations (LTs) in Japan, 10 LT facilities are accredited and good outcomes have been reported. A database review was conducted to clarify the impact of case volume at LT facilities in Japan on short- and long-term outcomes. Methods: All cadaveric LT cases treated between 2000 and 2021 in Japan were analyzed using the database of the Japanese Society of Lung and Heart-Lung Transplantation (JSLHT). The nine institutions represented were categorized into the low-volume (LV; <80 cumulative LT cases, <8 LTs/year, n=5) and high-volume (HV; ≥80 cumulative LT cases, ≥8 LTs/year, n=4) centers. Ninety-day and 1-year mortality, as well as 5- and 10-year survival data were evaluated. Results: A total of 658 cadaveric LTs were performed at the nine institutions. The 90-day rates of mortality at the HV and LV centers were 3.5% and 3.9%, respectively (P=0.801), while the 1-year mortality rates were 9.2% and 11.5%, respectively (P=0.199). Additionally, log-rank analysis of Kaplan-Meier curves showing case volume did not reveal a significant difference in long-term survival between the HV and LV centers (P=0.272), though the LV centers had wide differences for long-term outcomes (P=0.030). Conclusions: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers.
UR - http://www.scopus.com/inward/record.url?scp=85186600968&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85186600968&partnerID=8YFLogxK
U2 - 10.21037/jtd-23-90
DO - 10.21037/jtd-23-90
M3 - Article
AN - SCOPUS:85186600968
SN - 2072-1439
VL - 16
SP - 1473
EP - 1479
JO - Journal of Thoracic Disease
JF - Journal of Thoracic Disease
IS - 2
ER -