Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects

T. Kanbayashi; T. Sugiyama; R. Aizawa; Y. Saito; Y. Ogawa; T. Kitajima; Y. Kaneko; M. Abe; T. Shimizu

doi:10.1046/j.1440-1819.2002.01008.x

Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects

T. Kanbayashi, T. Sugiyama, R. Aizawa, Y. Saito, Y. Ogawa, T. Kitajima, Y. Kaneko, M. Abe, T. Shimizu

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Donepezil (Aricept) is a therapeutic drug for the treatment of Alzheimer's disease (AD). However, there have been only two reports describing the effects of donepezil on sleep as assessed by nocturnal polysomnography (PSG). With this in mind, the effects of donepezil on the sleep of healthy subjects was evaluated using PSG. The results indicated that the percentage of rapid eye movement sleep to total sleep time was increased significantly by a single dose of 5 mg of donepezil when given to healthy subjects immediately before retiring to bed.

Original language	English
Pages (from-to)	307-308
Number of pages	2
Journal	Psychiatry and clinical neurosciences
Volume	56
Issue number	3
DOIs	https://doi.org/10.1046/j.1440-1819.2002.01008.x
Publication status	Published - 2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Neuroscience
Neurology
Clinical Neurology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1046/j.1440-1819.2002.01008.x

Cite this

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title = "Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects",

abstract = "Donepezil (Aricept) is a therapeutic drug for the treatment of Alzheimer's disease (AD). However, there have been only two reports describing the effects of donepezil on sleep as assessed by nocturnal polysomnography (PSG). With this in mind, the effects of donepezil on the sleep of healthy subjects was evaluated using PSG. The results indicated that the percentage of rapid eye movement sleep to total sleep time was increased significantly by a single dose of 5 mg of donepezil when given to healthy subjects immediately before retiring to bed.",

author = "T. Kanbayashi and T. Sugiyama and R. Aizawa and Y. Saito and Y. Ogawa and T. Kitajima and Y. Kaneko and M. Abe and T. Shimizu",

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doi = "10.1046/j.1440-1819.2002.01008.x",

language = "English",

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T1 - Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects

AU - Kanbayashi, T.

AU - Sugiyama, T.

AU - Aizawa, R.

AU - Saito, Y.

AU - Ogawa, Y.

AU - Kitajima, T.

AU - Kaneko, Y.

AU - Abe, M.

AU - Shimizu, T.

PY - 2002

Y1 - 2002

N2 - Donepezil (Aricept) is a therapeutic drug for the treatment of Alzheimer's disease (AD). However, there have been only two reports describing the effects of donepezil on sleep as assessed by nocturnal polysomnography (PSG). With this in mind, the effects of donepezil on the sleep of healthy subjects was evaluated using PSG. The results indicated that the percentage of rapid eye movement sleep to total sleep time was increased significantly by a single dose of 5 mg of donepezil when given to healthy subjects immediately before retiring to bed.

AB - Donepezil (Aricept) is a therapeutic drug for the treatment of Alzheimer's disease (AD). However, there have been only two reports describing the effects of donepezil on sleep as assessed by nocturnal polysomnography (PSG). With this in mind, the effects of donepezil on the sleep of healthy subjects was evaluated using PSG. The results indicated that the percentage of rapid eye movement sleep to total sleep time was increased significantly by a single dose of 5 mg of donepezil when given to healthy subjects immediately before retiring to bed.

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ER -

Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects

Abstract

All Science Journal Classification (ASJC) codes

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