Effects of osmolality changes in nebulizar solutions on nasal mucosa

Mayumi Komori; Masato Miwa; Toshiko Mamiya; Yuka Kondo; Akihiko Takasu

doi:10.11453/orltokyo1958.42.Supplement2_181

Effects of osmolality changes in nebulizar solutions on nasal mucosa

Mayumi Komori, Masato Miwa, Toshiko Mamiya, Yuka Kondo, Akihiko Takasu

Department of Otolaryngology ・ Head and Neck Surgery

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The effects of osmolarity changes in nebulizer solutions on nasal mucosa was not known clearly. We measured nasal airway resistance, total nasal volume, weight of nasal drop and nasal mucociliay clearance by saccharin granule technique during the aerosol administration. The contents of nebulizer solutions were distilled water, physiological saline solution and 10% saline solution. Mucociliary clearance were improved in each concentration of solutions. Total nasal volume, nasal airway resistance and weight of nasal drop increased after inhalation of hypertonic saline. These results suggest osmolarity changes of nebulizer solutions affect mucociliary clearance and nasal mucosal swelling.

Original language	English
Pages (from-to)	181-185
Number of pages	5
Journal	JIBI INKOKA TEMBO
Volume	42
DOIs	https://doi.org/10.11453/orltokyo1958.42.Supplement2_181
Publication status	Published - 1999

All Science Journal Classification (ASJC) codes

Otorhinolaryngology

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10.11453/orltokyo1958.42.Supplement2_181

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title = "Effects of osmolality changes in nebulizar solutions on nasal mucosa",

abstract = "The effects of osmolarity changes in nebulizer solutions on nasal mucosa was not known clearly. We measured nasal airway resistance, total nasal volume, weight of nasal drop and nasal mucociliay clearance by saccharin granule technique during the aerosol administration. The contents of nebulizer solutions were distilled water, physiological saline solution and 10% saline solution. Mucociliary clearance were improved in each concentration of solutions. Total nasal volume, nasal airway resistance and weight of nasal drop increased after inhalation of hypertonic saline. These results suggest osmolarity changes of nebulizer solutions affect mucociliary clearance and nasal mucosal swelling.",

author = "Mayumi Komori and Masato Miwa and Toshiko Mamiya and Yuka Kondo and Akihiko Takasu",

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AU - Takasu, Akihiko

PY - 1999

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AB - The effects of osmolarity changes in nebulizer solutions on nasal mucosa was not known clearly. We measured nasal airway resistance, total nasal volume, weight of nasal drop and nasal mucociliay clearance by saccharin granule technique during the aerosol administration. The contents of nebulizer solutions were distilled water, physiological saline solution and 10% saline solution. Mucociliary clearance were improved in each concentration of solutions. Total nasal volume, nasal airway resistance and weight of nasal drop increased after inhalation of hypertonic saline. These results suggest osmolarity changes of nebulizer solutions affect mucociliary clearance and nasal mucosal swelling.

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Effects of osmolality changes in nebulizar solutions on nasal mucosa

Abstract

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