TY - JOUR
T1 - Effects of osmolality changes in nebulizar solutions on nasal mucosa
AU - Komori, Mayumi
AU - Miwa, Masato
AU - Mamiya, Toshiko
AU - Kondo, Yuka
AU - Takasu, Akihiko
PY - 1999
Y1 - 1999
N2 - The effects of osmolarity changes in nebulizer solutions on nasal mucosa was not known clearly. We measured nasal airway resistance, total nasal volume, weight of nasal drop and nasal mucociliay clearance by saccharin granule technique during the aerosol administration. The contents of nebulizer solutions were distilled water, physiological saline solution and 10% saline solution. Mucociliary clearance were improved in each concentration of solutions. Total nasal volume, nasal airway resistance and weight of nasal drop increased after inhalation of hypertonic saline. These results suggest osmolarity changes of nebulizer solutions affect mucociliary clearance and nasal mucosal swelling.
AB - The effects of osmolarity changes in nebulizer solutions on nasal mucosa was not known clearly. We measured nasal airway resistance, total nasal volume, weight of nasal drop and nasal mucociliay clearance by saccharin granule technique during the aerosol administration. The contents of nebulizer solutions were distilled water, physiological saline solution and 10% saline solution. Mucociliary clearance were improved in each concentration of solutions. Total nasal volume, nasal airway resistance and weight of nasal drop increased after inhalation of hypertonic saline. These results suggest osmolarity changes of nebulizer solutions affect mucociliary clearance and nasal mucosal swelling.
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U2 - 10.11453/orltokyo1958.42.Supplement2_181
DO - 10.11453/orltokyo1958.42.Supplement2_181
M3 - Article
AN - SCOPUS:85009596275
VL - 42
SP - 181
EP - 185
JO - Oto-Rhino-Laryngology Tokyo
JF - Oto-Rhino-Laryngology Tokyo
SN - 0386-9687
ER -