Effects of ovariectomy on parafollicular cells in the rat

Kazuyoshi Sakai, Shizuko Yamada, Keiki Yamada

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Changes in the parafollicular cells in the thyroid gland of orariectomized rats were investigated to clarify the relationship between the secretory function of sex hormones and that of parafollicular cells. Compared with control rats, the ovariectomized rats exhibited decreases in 1) the number of parafollicular cells in the thyroid glands, 2) the number of secretory granules in the parafollicular cells, and 3) the area occupied by the Golgi complex. These results suggest that the lack of estrogen caused by ovariectomy reduces the synthesis and release of calcitonin in parafollicular cells, which may be one of the causes of osteoporosis.

Original languageEnglish
Pages (from-to)311-320
Number of pages10
JournalOkajimas Folia Anatomica Japonica
Issue number6
Publication statusPublished - 03-2000

All Science Journal Classification (ASJC) codes

  • Anatomy


Dive into the research topics of 'Effects of ovariectomy on parafollicular cells in the rat'. Together they form a unique fingerprint.

Cite this