Effects of transcutaneous spinal DC stimulation on plasticity of the spinal circuits and corticospinal tracts in humans

Tomofumi Yamaguchi; Shuhei Fujimoto; Yohei Otaka; Satoshi Tanaka

doi:10.1109/NER.2013.6695925

Effects of transcutaneous spinal DC stimulation on plasticity of the spinal circuits and corticospinal tracts in humans

Tomofumi Yamaguchi
, Shuhei Fujimoto
, Yohei Otaka
, Satoshi Tanaka

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

9 Citations (Scopus)

Abstract

The aim of this exploratory study was to investigate the effects of transcutaneous spinal direct current stimulation (tsDCS) on the plasticity of spinal circuits and corticospinal tracts in humans. Ten healthy volunteers participated in this single-blind, sham-controlled cross-over study. Reciprocal inhibition and D1 inhibition of the soleus H-reflex (experiment 1), and motor evoked potentials (MEPs) of the tibialis anterior and soleus muscles induced by transcranial magnetic stimulation over the motor cortex (experiment 2) were recorded before and after anodal tsDCS (2 mA, 15 min) or sham (2 mA, 15 sec) delivered at the thoracic spine level. In experiment 1, anodal tsDCS significantly decreased the amount of D1 inhibition at least 15 min after the end of stimulation, but did not affect the amount of reciprocal inhibition. In experiment 2, anodal tsDCS did not affect the amplitude of MEPs. The present results provide further evidence that tsDCS can induce short-term plasticity in human spinal reflex circuits.

Original language	English
Title of host publication	2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
Pages	275-278
Number of pages	4
DOIs	https://doi.org/10.1109/NER.2013.6695925
Publication status	Published - 2013
Externally published	Yes
Event	2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 - San Diego, CA, United States Duration: 06-11-2013 → 08-11-2013

Publication series

Name	International IEEE/EMBS Conference on Neural Engineering, NER
ISSN (Print)	1948-3546
ISSN (Electronic)	1948-3554

Other

Other	2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
Country/Territory	United States
City	San Diego, CA
Period	06-11-13 → 08-11-13

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Artificial Intelligence
Mechanical Engineering

Access to Document

10.1109/NER.2013.6695925

Cite this

Yamaguchi, T., Fujimoto, S., Otaka, Y., & Tanaka, S. (2013). Effects of transcutaneous spinal DC stimulation on plasticity of the spinal circuits and corticospinal tracts in humans. In 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 (pp. 275-278). Article 6695925 (International IEEE/EMBS Conference on Neural Engineering, NER). https://doi.org/10.1109/NER.2013.6695925

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abstract = "The aim of this exploratory study was to investigate the effects of transcutaneous spinal direct current stimulation (tsDCS) on the plasticity of spinal circuits and corticospinal tracts in humans. Ten healthy volunteers participated in this single-blind, sham-controlled cross-over study. Reciprocal inhibition and D1 inhibition of the soleus H-reflex (experiment 1), and motor evoked potentials (MEPs) of the tibialis anterior and soleus muscles induced by transcranial magnetic stimulation over the motor cortex (experiment 2) were recorded before and after anodal tsDCS (2 mA, 15 min) or sham (2 mA, 15 sec) delivered at the thoracic spine level. In experiment 1, anodal tsDCS significantly decreased the amount of D1 inhibition at least 15 min after the end of stimulation, but did not affect the amount of reciprocal inhibition. In experiment 2, anodal tsDCS did not affect the amplitude of MEPs. The present results provide further evidence that tsDCS can induce short-term plasticity in human spinal reflex circuits.",

author = "Tomofumi Yamaguchi and Shuhei Fujimoto and Yohei Otaka and Satoshi Tanaka",

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doi = "10.1109/NER.2013.6695925",

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series = "International IEEE/EMBS Conference on Neural Engineering, NER",

pages = "275--278",

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Yamaguchi, T, Fujimoto, S, Otaka, Y & Tanaka, S 2013, Effects of transcutaneous spinal DC stimulation on plasticity of the spinal circuits and corticospinal tracts in humans. in 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013., 6695925, International IEEE/EMBS Conference on Neural Engineering, NER, pp. 275-278, 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013, San Diego, CA, United States, 06-11-13. https://doi.org/10.1109/NER.2013.6695925

Effects of transcutaneous spinal DC stimulation on plasticity of the spinal circuits and corticospinal tracts in humans. / Yamaguchi, Tomofumi; Fujimoto, Shuhei; Otaka, Yohei et al.
2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013. 2013. p. 275-278 6695925 (International IEEE/EMBS Conference on Neural Engineering, NER).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - The aim of this exploratory study was to investigate the effects of transcutaneous spinal direct current stimulation (tsDCS) on the plasticity of spinal circuits and corticospinal tracts in humans. Ten healthy volunteers participated in this single-blind, sham-controlled cross-over study. Reciprocal inhibition and D1 inhibition of the soleus H-reflex (experiment 1), and motor evoked potentials (MEPs) of the tibialis anterior and soleus muscles induced by transcranial magnetic stimulation over the motor cortex (experiment 2) were recorded before and after anodal tsDCS (2 mA, 15 min) or sham (2 mA, 15 sec) delivered at the thoracic spine level. In experiment 1, anodal tsDCS significantly decreased the amount of D1 inhibition at least 15 min after the end of stimulation, but did not affect the amount of reciprocal inhibition. In experiment 2, anodal tsDCS did not affect the amplitude of MEPs. The present results provide further evidence that tsDCS can induce short-term plasticity in human spinal reflex circuits.

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Effects of transcutaneous spinal DC stimulation on plasticity of the spinal circuits and corticospinal tracts in humans

Abstract

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