TY - JOUR
T1 - Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects
AU - Aizawa, Rika
AU - Kanbayashi, Takashi
AU - Saito, Yasushi
AU - Ogawa, Yuriko
AU - Sugiyama, Tomonari
AU - Kitajima, Tsuyoshi
AU - Kaneko, Yoshihiko
AU - Abe, Masahito
AU - Shimizu, Tetsuo
PY - 2002
Y1 - 2002
N2 - Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using the double-blind method. Yoku-kan-san-ka-chimpi-hange increased the total sleep time significantly, and tended to cause an increase in sleep efficiency and of stage 2 sleep, as well as a decrease of sleep latency and of stage 3 + 4 sleep. There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines.
AB - Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using the double-blind method. Yoku-kan-san-ka-chimpi-hange increased the total sleep time significantly, and tended to cause an increase in sleep efficiency and of stage 2 sleep, as well as a decrease of sleep latency and of stage 3 + 4 sleep. There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines.
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U2 - 10.1046/j.1440-1819.2002.01006.x
DO - 10.1046/j.1440-1819.2002.01006.x
M3 - Article
C2 - 12047606
AN - SCOPUS:0036317812
SN - 1323-1316
VL - 56
SP - 303
EP - 304
JO - Psychiatry and clinical neurosciences
JF - Psychiatry and clinical neurosciences
IS - 3
ER -
