Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects

Rika Aizawa, Takashi Kanbayashi, Yasushi Saito, Yuriko Ogawa, Tomonari Sugiyama, Tsuyoshi Kitajima, Yoshihiko Kaneko, Masahito Abe, Tetsuo Shimizu

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using the double-blind method. Yoku-kan-san-ka-chimpi-hange increased the total sleep time significantly, and tended to cause an increase in sleep efficiency and of stage 2 sleep, as well as a decrease of sleep latency and of stage 3 + 4 sleep. There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines.

Original languageEnglish
Pages (from-to)303-304
Number of pages2
JournalPsychiatry and clinical neurosciences
Volume56
Issue number3
DOIs
Publication statusPublished - 22-07-2002

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Healthy Volunteers
Sleep
Sleep Stages
Polysomnography
Herbal Medicine
REM Sleep
Sleep Initiation and Maintenance Disorders
Traditional Medicine
Eye Movements
Benzodiazepines
Double-Blind Method
yokukansankachimpihange
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Aizawa, Rika ; Kanbayashi, Takashi ; Saito, Yasushi ; Ogawa, Yuriko ; Sugiyama, Tomonari ; Kitajima, Tsuyoshi ; Kaneko, Yoshihiko ; Abe, Masahito ; Shimizu, Tetsuo. / Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects. In: Psychiatry and clinical neurosciences. 2002 ; Vol. 56, No. 3. pp. 303-304.
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Aizawa, R, Kanbayashi, T, Saito, Y, Ogawa, Y, Sugiyama, T, Kitajima, T, Kaneko, Y, Abe, M & Shimizu, T 2002, 'Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects', Psychiatry and clinical neurosciences, vol. 56, no. 3, pp. 303-304. https://doi.org/10.1046/j.1440-1819.2002.01006.x

Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects. / Aizawa, Rika; Kanbayashi, Takashi; Saito, Yasushi; Ogawa, Yuriko; Sugiyama, Tomonari; Kitajima, Tsuyoshi; Kaneko, Yoshihiko; Abe, Masahito; Shimizu, Tetsuo.

In: Psychiatry and clinical neurosciences, Vol. 56, No. 3, 22.07.2002, p. 303-304.

Research output: Contribution to journalArticle

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AU - Aizawa, Rika

AU - Kanbayashi, Takashi

AU - Saito, Yasushi

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AU - Sugiyama, Tomonari

AU - Kitajima, Tsuyoshi

AU - Kaneko, Yoshihiko

AU - Abe, Masahito

AU - Shimizu, Tetsuo

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