Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor

Yoji Sasaki, Yasumasa Niwa, Nobuhiro Ando, Yasuro Otsuka, Naoki Ohmiya, Yoshiki Hirooka, Akihiro Itoh, Shimako Furuta, Hiderni Goto

Research output: Contribution to journalArticle

Abstract

A 65-year-old man was referred to our hospital for evaluation of his huge abdominal tumor. He was diagnosed as having a gastrointestinal stromal tumor arising from the stomach. Seven months after surgery, multiple liver metastases and mesenteric dissemination occurred. He was medicated with STI571, which works by blocking proliferation of malignant cells with expression of c-kit. The tumors shrank and serum lactate dehydrogenase and alkaline phosphatase concentrations fell to below the normal limit three months later. STI571 was effective medicine for the metastatic gastrointestinal stromal tumor for six months in this case.

Original languageEnglish
Pages (from-to)1764-1767
Number of pages4
JournalHepato-Gastroenterology
Volume52
Issue number66
Publication statusPublished - 01-11-2005
Externally publishedYes

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Gastrointestinal Stromal Tumors
L-Lactate Dehydrogenase
Alkaline Phosphatase
Neoplasms
Stomach
Cell Proliferation
Neoplasm Metastasis
Liver
Serum
Imatinib Mesylate

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Hepatology
  • Gastroenterology

Cite this

Sasaki, Y., Niwa, Y., Ando, N., Otsuka, Y., Ohmiya, N., Hirooka, Y., ... Goto, H. (2005). Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor. Hepato-Gastroenterology, 52(66), 1764-1767.
Sasaki, Yoji ; Niwa, Yasumasa ; Ando, Nobuhiro ; Otsuka, Yasuro ; Ohmiya, Naoki ; Hirooka, Yoshiki ; Itoh, Akihiro ; Furuta, Shimako ; Goto, Hiderni. / Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor. In: Hepato-Gastroenterology. 2005 ; Vol. 52, No. 66. pp. 1764-1767.
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Sasaki, Y, Niwa, Y, Ando, N, Otsuka, Y, Ohmiya, N, Hirooka, Y, Itoh, A, Furuta, S & Goto, H 2005, 'Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor', Hepato-Gastroenterology, vol. 52, no. 66, pp. 1764-1767.

Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor. / Sasaki, Yoji; Niwa, Yasumasa; Ando, Nobuhiro; Otsuka, Yasuro; Ohmiya, Naoki; Hirooka, Yoshiki; Itoh, Akihiro; Furuta, Shimako; Goto, Hiderni.

In: Hepato-Gastroenterology, Vol. 52, No. 66, 01.11.2005, p. 1764-1767.

Research output: Contribution to journalArticle

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AU - Ando, Nobuhiro

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AU - Hirooka, Yoshiki

AU - Itoh, Akihiro

AU - Furuta, Shimako

AU - Goto, Hiderni

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Sasaki Y, Niwa Y, Ando N, Otsuka Y, Ohmiya N, Hirooka Y et al. Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor. Hepato-Gastroenterology. 2005 Nov 1;52(66):1764-1767.