Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor

Yoji Sasaki; Yasumasa Niwa; Nobuhiro Ando; Yasuro Otsuka; Naoki Ohmiya; Yoshiki Hirooka; Akihiro Itoh; Shimako Furuta; Hiderni Goto

Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor

Yoji Sasaki, Yasumasa Niwa, Nobuhiro Ando, Yasuro Otsuka, Naoki Ohmiya, Yoshiki Hirooka, Akihiro Itoh, Shimako Furuta, Hiderni Goto

Research output: Contribution to journal › Article › peer-review

Abstract

A 65-year-old man was referred to our hospital for evaluation of his huge abdominal tumor. He was diagnosed as having a gastrointestinal stromal tumor arising from the stomach. Seven months after surgery, multiple liver metastases and mesenteric dissemination occurred. He was medicated with STI571, which works by blocking proliferation of malignant cells with expression of c-kit. The tumors shrank and serum lactate dehydrogenase and alkaline phosphatase concentrations fell to below the normal limit three months later. STI571 was effective medicine for the metastatic gastrointestinal stromal tumor for six months in this case.

Original language	English
Pages (from-to)	1764-1767
Number of pages	4
Journal	Hepato-gastroenterology
Volume	52
Issue number	66
Publication status	Published - 11-2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Hepatology
Gastroenterology

Cite this

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title = "Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor",

abstract = "A 65-year-old man was referred to our hospital for evaluation of his huge abdominal tumor. He was diagnosed as having a gastrointestinal stromal tumor arising from the stomach. Seven months after surgery, multiple liver metastases and mesenteric dissemination occurred. He was medicated with STI571, which works by blocking proliferation of malignant cells with expression of c-kit. The tumors shrank and serum lactate dehydrogenase and alkaline phosphatase concentrations fell to below the normal limit three months later. STI571 was effective medicine for the metastatic gastrointestinal stromal tumor for six months in this case.",

author = "Yoji Sasaki and Yasumasa Niwa and Nobuhiro Ando and Yasuro Otsuka and Naoki Ohmiya and Yoshiki Hirooka and Akihiro Itoh and Shimako Furuta and Hiderni Goto",

year = "2005",

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language = "English",

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journal = "Hepato-gastroenterology",

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T1 - Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor

AU - Sasaki, Yoji

AU - Niwa, Yasumasa

AU - Ando, Nobuhiro

AU - Otsuka, Yasuro

AU - Ohmiya, Naoki

AU - Hirooka, Yoshiki

AU - Itoh, Akihiro

AU - Furuta, Shimako

AU - Goto, Hiderni

PY - 2005/11

Y1 - 2005/11

N2 - A 65-year-old man was referred to our hospital for evaluation of his huge abdominal tumor. He was diagnosed as having a gastrointestinal stromal tumor arising from the stomach. Seven months after surgery, multiple liver metastases and mesenteric dissemination occurred. He was medicated with STI571, which works by blocking proliferation of malignant cells with expression of c-kit. The tumors shrank and serum lactate dehydrogenase and alkaline phosphatase concentrations fell to below the normal limit three months later. STI571 was effective medicine for the metastatic gastrointestinal stromal tumor for six months in this case.

AB - A 65-year-old man was referred to our hospital for evaluation of his huge abdominal tumor. He was diagnosed as having a gastrointestinal stromal tumor arising from the stomach. Seven months after surgery, multiple liver metastases and mesenteric dissemination occurred. He was medicated with STI571, which works by blocking proliferation of malignant cells with expression of c-kit. The tumors shrank and serum lactate dehydrogenase and alkaline phosphatase concentrations fell to below the normal limit three months later. STI571 was effective medicine for the metastatic gastrointestinal stromal tumor for six months in this case.

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M3 - Article

C2 - 16334774

AN - SCOPUS:28544440615

SN - 0172-6390

VL - 52

SP - 1764

EP - 1767

JO - Hepato-gastroenterology

JF - Hepato-gastroenterology

IS - 66

ER -

Efficacy of STI571 for a patient with metastatic gastrointestinal stromal tumor

Abstract

All Science Journal Classification (ASJC) codes

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