Background: We previously reported a new system of electroretinographic monitoring of the retinal function during vitrectomy in human eyes, and found that lowering the intravitreal temperature by applying an infusion solution kept at room temperature (used routinely for vitrectomy throughout the world) can alter the electroretinogram (ERG). This time we attempted to study the effect upon the ERG of replacing the intraocular medium and acutely elevating the intraocular pressure during vitrectomy. Methods: Using a special contact lens with a built-in light-emitting diode light source, 30-Hz flicker ERG was quickly recorded under aseptic conditions. Results: Acute, reversible reduction in amplitude was observed upon replacing the intraocular medium with air or silicone oil and during periods of acutely elevated intraocular pressure. Infusions of gentamicin or miconazole did not affect the ERG when intravitreal temperature and intraocular pressure were constant. Conclusion: The ERG monitor can reveal changes of the retinal function during vitrectomy, particularly when the infusion temperature, intraocular medium and intraocular pressure are kept constant.
|Number of pages||5|
|Journal||Graefe's Archive for Clinical and Experimental Ophthalmology|
|Publication status||Published - 01-1998|
All Science Journal Classification (ASJC) codes
- Sensory Systems
- Cellular and Molecular Neuroscience