Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals

H. Arai; T. Nakagawa; Y. I. Kosaka; M. Higuchi; T. Matsui; N. Okamura; M. Tashiro; H. Sasaki

Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals

H. Arai, T. Nakagawa, Y. I. Kosaka, M. Higuchi, T. Matsui, N. Okamura, M. Tashiro, H. Sasaki

Research output: Contribution to journal › Article › peer-review

Abstract

In order to investigate whether measurement of cerebrospinal fluid tau (CSF-tau) protein levels serves to detect Alzheimer's disease (AD) in its incipient stages, the CSF-tau levels were examined in 15 memory-impaired, but non-demented individuals. In 10 patients who later progressed to develop AD, the entry CSF-tau levels were significantly increased compared to five patients who remained non-demented during follow-up. Elevated CSF-tau levels may therefore serve as a predictor of progression to dementia consistent with AD.

Original language	English
Pages (from-to)	211-213
Number of pages	3
Journal	Alzheimer's Research
Volume	3
Issue number	5
Publication status	Published - 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Neuroscience
Neuropsychology and Physiological Psychology

Cite this

@article{05fafa59f8994ff9852daa18426871b4,

title = "Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals",

abstract = "In order to investigate whether measurement of cerebrospinal fluid tau (CSF-tau) protein levels serves to detect Alzheimer's disease (AD) in its incipient stages, the CSF-tau levels were examined in 15 memory-impaired, but non-demented individuals. In 10 patients who later progressed to develop AD, the entry CSF-tau levels were significantly increased compared to five patients who remained non-demented during follow-up. Elevated CSF-tau levels may therefore serve as a predictor of progression to dementia consistent with AD.",

author = "H. Arai and T. Nakagawa and Kosaka, {Y. I.} and M. Higuchi and T. Matsui and N. Okamura and M. Tashiro and H. Sasaki",

year = "1997",

language = "English",

volume = "3",

pages = "211--213",

journal = "Alzheimer's Research",

issn = "1356-918X",

publisher = "Rapid Science Publishers",

number = "5",

}

TY - JOUR

T1 - Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals

AU - Arai, H.

AU - Nakagawa, T.

AU - Kosaka, Y. I.

AU - Higuchi, M.

AU - Matsui, T.

AU - Okamura, N.

AU - Tashiro, M.

AU - Sasaki, H.

PY - 1997

Y1 - 1997

N2 - In order to investigate whether measurement of cerebrospinal fluid tau (CSF-tau) protein levels serves to detect Alzheimer's disease (AD) in its incipient stages, the CSF-tau levels were examined in 15 memory-impaired, but non-demented individuals. In 10 patients who later progressed to develop AD, the entry CSF-tau levels were significantly increased compared to five patients who remained non-demented during follow-up. Elevated CSF-tau levels may therefore serve as a predictor of progression to dementia consistent with AD.

AB - In order to investigate whether measurement of cerebrospinal fluid tau (CSF-tau) protein levels serves to detect Alzheimer's disease (AD) in its incipient stages, the CSF-tau levels were examined in 15 memory-impaired, but non-demented individuals. In 10 patients who later progressed to develop AD, the entry CSF-tau levels were significantly increased compared to five patients who remained non-demented during follow-up. Elevated CSF-tau levels may therefore serve as a predictor of progression to dementia consistent with AD.

UR - http://www.scopus.com/inward/record.url?scp=0030698647&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030698647&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0030698647

SN - 1356-918X

VL - 3

SP - 211

EP - 213

JO - Alzheimer's Research

JF - Alzheimer's Research

IS - 5

ER -

Elevated cerebrospinal fluid tau protein level as a predictor of dementia in memory-impaired individuals

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this